The Risks of Mixing Dramamine and Alcohol
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Nobody likes to feel nauseous. It’s that indescribable feeling — not quite “pain” but somehow just as bad. And often there seems to be no escape from it. Philosopher Jean-Paul Sartre dedicated a whole novel — Nausea — to the pervasive sensation. He writes, “The nausea has not left me and I don't believe it will leave me so soon; but I no longer have to bear it, it is no longer an illness or a passing fit: it is I.”
So if you tend to get nauseous — on planes, buses, that spinning teacup ride at Disney World — you probably have your travel kit stocked with over-the-counter nausea aids (if only they were around when Sartre’s protagonist was grappling with his affliction!).
But wait a second, is it okay to pop a Dramamine before knocking back a glass of wine on the plane or have a beer after you get off that bumpy bus ride? What are the dangers of mixing Dramamine and alcohol — can you drink on Dramamine at all? And what about using Dramamine for hangover-related nausea? Let’s find out more!
Unfortunately, motion sickness is a part of life for many of us. It can show up during our daily commute to work, in the back seat of an Uber, and even on vacation trips. As scientist Natasha Tuznik tells UC Davis Health, “A study conducted in 2019 found that almost everyone has experienced or will experience motion sickness at some point in their lifetime.”
This “sickness” goes way back — in fact, the word comes from the Greek naus, meaning “ship.” These days, of course, there are many other modes of transportation that seem to conspire to ruin our transit experience.
In a study published in Ergonomics, as many as 28.4% of people surveyed reported feeling ill during a total of 110 hours of test drives that included 5 types of vehicles and 17 different drivers. Moreover, 12.8% reported experiencing nausea, while 1.7% brave participants admitted to “losing their lunch” during the experiment!
Riding in cars is part of modern life. Thankfully, so is modern science! Enter: Dramamine.
Dramamine (Dimenhydrinate) is an antihistamine used to kick the most unpleasant symptoms of motion sickness (such as nausea, vomiting, and dizziness) right to the curb. In fact, it can even prevent them from starting in the first place!
Know Dramamine by another name? That’s quite possible. According to ScienceDirect, this trusty travel companion has many aliases:
Phew! That’s quite a list. Whichever alias you know it by, they all work the same way — and the mechanism is pretty clever!
Dramamine helps our body maintain a sense of balance during those bumpy bus rides and turbulent takeovers. It works by blocking certain signals in the brain that trigger these uncomfortable symptoms, providing much-needed relief during travel. While taking a pill when symptoms kick in is an option (it’s never too late!), many travelers opt for taking the precaution of popping one an hour or so before even getting on the bus (or plane, or car).
As for dosage, the standard for adults is 50-100 mg every 4-6 hours, with 400 mg per day being the limit.
While Dramamine is all about reducing the unpleasant “side effects” of travel, it comes with a bit of baggage of its own. The common side effects are usually pretty mild:
So what happens when we add alcohol to the mix? There are a couple of reasons why the two are not great “travel companions”:
Dramamine can make us drowsy on its own, but with alcohol in the picture, the effect gets much more pronounced — sometimes to a dangerous degree. As a depressant, alcohol numbs our senses and slows cognitive processing while impairing our motor skills.
The reason has to do with the way it affects our brain chemistry. Alcohol tends to increase the activity of GABA, an inhibitory neurotransmitter that slows down the nervous system, while simultaneously toning down the effects of glutamate, its “excitatory” counterpart. The result? Our reflexes take a hit, our cognitive abilities are dulled, and we feel drowsy.
The booze-dramamine combo can dangerously enhance impairment, raising the risk of accidents and injuries, especially in activities requiring alertness, such as driving. However, even if we’re not behind the wheel, the extra grogginess can get in the way. (After all, nobody wants to miss their connecting flight!) And if we end up having several drinks, we could get into dangerous waters by slowing down our central nervous system so much that it becomes a health risk.
Alcohol is notorious for leaving us parched and depleted of electrolytes, and adding Dramamine to the mix can make things worse. This dehydrating duo will leave you twice as thirsty — especially after a long plane ride!
Mixing alcohol and Dramamine can also worsen other side effects, such as dry mouth, blurred vision, and dizziness. If we’re already feeling drowsy, this could really spell trouble, especially for those of us who are a bit older.
You might be wondering, “How long after taking Dramamine can I drink alcohol?” The effects of the medication can last from 4 to 6 hours, and it takes about 1 to 3 hours for its peak effects to show up. Given its half-life, it's best to wait at least 24 hours after taking Dramamine before drinking so your body can fully process the medication. Waiting an extra few hours might reduce the risk of adverse interactions even more.
Is one drink okay to have with Dramamine? Not really. Even one drink can significantly increase the side effects and amp up the risks, so it's best to skip booze entirely until the medication has cleared from your system.
Given that nausea is a common hangover symptom, it seems that it would make sense to reach for a Dramamine pill for relief.
But is it a good idea? Not so much.
It’s true that Dramamine can potentially alleviate some symptoms of a hangover, such as nausea and a sense of balance disruption. However, Dramamine’s sedative effects can add to the grogginess and cognitive fuzziness often experienced during a hangover.
Moreover, taking Dramamine to combat hangover symptoms can be risky if alcohol is still present in the system. The combination can lead to increased drowsiness, dehydration, and further impairment of judgment and motor skills.
Moreover, it’s also worth noting that while Dramamine tends to be safe for many people when it comes to potential misuse, for some it’s been known to be habit-forming (sometimes very much so — we’re talking large daily doses). If we have a history of substance misuse, it’s important to be careful and mindful about our Dramamine intake.
Finally, many of us might have noticed that Dramamine has a travel partner that usually shares the same shelf in the drug store — Bonine. Is this a better choice to take along for the ride if we know we might drink?
Bonine (meclizine) is also marketed as a motion sickness aid but one that claims to work all day — as opposed to Dramamine’s 4- to 6-hour window. Unfortunately for those who might have been hoping Bonine could work as a booze-friendly alternative to Dramamine, this isn’t the case. Bonine shares the same risk of central nervous system suppression — along with increased dehydration and intensified side effects.
To ensure safety, it’s best to avoid alcohol when taking any motion sickness medication.
Ready for some tips on how to relieve nausea and hangovers more effectively (and maybe prevent them altogether)? Here we go!
If you’re finding that alcohol is taking up a bit too much air time in your life in general — whether or not Dramamine is part of the picture — here are some additional tips for the journey.
Nausea is, unfortunately, a part of life, and it’s great that Dramamine is here to help. But the not-so-helpful interactions between this medication and alcohol don’t have to be part of your journey. Happy booze-free, hangover-free travels!
1. What is Dramamine?
Dramamine (Dimenhydrinate) is an antihistamine used to treat nausea related to motion sickness.
2. Can you drink on Dramamine?
It’s not advisable to mix alcohol and Dramamine. For one thing, both suppress the nervous system, and it could be dangerous to intensify this effect. Also, Dramamine and alcohol are both dehydrating, so mixing the two can make dehydration even more severe. Finally, alcohol could intensify the side effects of Dramamine, such as dry mouth and dizziness.
3. Does Dramamine help a hangover?
It’s not a great idea to use Dramamine for hangovers, since alcohol could still be in your system. It might compound the effects, making the discomfort worse.
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