Interaction of Vyvanse With Alcohol
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It’s a typical Saturday night. You’re at your favorite Japanese restaurant, and when the waiter comes to take your order, you rattle off, “Miso salmon, a side of broccoli and rice, and a glass of …” You’re about to order your usual red, but then you remember that you’re taking Vyvanse — a medication commonly prescribed for attention-deficit/hyperactivity disorder (ADHD). Can you drink on Vyvanse? Is drinking on Vyvanse dangerous? Let’s explore!
Attention deficit and hyperactivity disorder (ADHD) is a familiar term today, but what does it mean? In The Lightning Thief, Rick Riordan describes it as a superpower: “Taken together, it’s almost a sure sign. The letters float off the page when we read, right? That’s because your mind is hardwired for ancient Greek. And the ADHD — we’re impulsive, can’t sit still in the classroom. That’s your battlefield reflexes. In a real fight, they’d keep you alive. As for the attention problems, that’s because you see too much, Percy, not too little. Your senses are better than a regular mortal’s.”
While this way of seeing ADHD is refreshingly optimistic, the condition actually can be a burden. Those with ADHD daydream, unintentionally interrupt others when a sudden idea strikes, fidget with their hair or phone, and leave the laundry they’re folding half-done to reorganize the kitchen cupboards. You get the picture — ADHD can get in the way of living for children and adults alike.
From a neuroscience perspective, the problems with attention are the result of a communication glitch between the decision-making prefrontal cortex and the striatum, which is involved in attention. So, as we can see, the term “attention deficit” is a bit of a misnomer: there’s no “lack” of attention; we just focus on the “wrong” thing. The hyperactivity part, in turn, has more to do with differences in the dopamine-driven reward system that makes it difficult for people with ADHD to stay motivated without external stimulation.
The use of medication to treat the symptoms of ADHD remains somewhat controversial, but for many, medication has proved effective in easing the symptoms.
Historically, the first line of medication treatment for ADHD comprise stimulants — drugs that speed up the nervous system, such as Adderall and Ritalin. While generally sanctioned by the medical community as a viable solution for some, a major source of concern with stimulants has been the risk of dependency. As a result, the FDA regulates them with gusto (and with good reason — there have been many cases of addiction, overdose, and even death caused by stimulants over the years).
Enter Vyvanse. Unlike other stimulants, Vyvanse is a prodrug, which means it only becomes active once it's gradually metabolized by the body. The result? It has the effects of other stimulants but potentially reduces abuse risk since it doesn’t provide the same energy boost that many find so enticing (and ultimately counterproductive).
But what about drinking on Vyvanse? As it turns out, we’re better off opting out to avoid some unpleasant surprises. Let’s explore why mixing Vyvanse and alcohol isn’t a good idea.
First of all, there’s the issue of side effects, many of which can be amped up by alcohol. According to Drugs.com, common Vyvanse side effects include the typical ones we would expect from stimulants:
As we can see, the side effects of Vyvanse and alcohol don’t mix well. But there are other reasons why it’s wise to avoid the combination.
As a stimulant, Vyvanse increases neurotransmitter activity in the brain, which can boost energy and alertness. When we mix it with booze — a depressant — two not-so great things happen:
Our heart does a lot of work for us every second of our lives. Let’s give it the care it deserves (while also avoiding the pitfalls of the masking effect). The risk just isn’t worth it.
One of the most serious risks of mixing Vyvanse and alcohol is the risk of dependency. While the risk is lower than it is in fast-acting drugs such as Adderall, Vyvanse still causes dopamine release. Since alcohol does the same — and since artificial dopamine boosts can cause unnatural spikes in feelings of reward and pleasure — we can find ourselves at risk of addiction and substance misuse.
Moreover, alcohol can lower inhibitions and impair judgment — a concern significant for those of us dealing with ADHD. The combination with Vyvanse might lead to increased impulsivity and poor decision making, resulting in risky behaviors.
When it comes to ADHD symptoms, alcohol is counterproductive, to say the least. Anyone who has tried to have a focused conversation with a friend who’s had a few too many knows how it’s often a lost cause. Likewise, trying to get a tipsy group of people to go somewhere together can feel like herding cats: their attention spans get worse by the minute, and their ability to focus can seem virtually nonexistent.
By slowing down activity in the prefrontal cortex, alcohol gets in the way of our ability to think logically and stay focused. Moreover, it tends to lead to so-called “alcohol myopia” — a tendency to focus on the most salient (i.e., “juiciest”) aspect of a subject or scene while ignoring everything else. This tendency to hyperfocus on whatever grabs our attention is exactly what we’re already fighting against if we have ADHD. The whole point of taking medications such as Vyvanse is to put the prefrontal cortex back in the driver’s seat — and alcohol makes that harder.
Perhaps you’re thinking, “How long after taking Vyvanse can I drink alcohol?” According to scientists and doctors, the best approach is to avoid alcohol completely while you’re on Vyvanse. You will eliminate the risk of adverse interactions and set yourself up for success when it comes to managing your symptoms.
That said, if you do choose to drink, healthcare providers advise waiting at least 14 hours, which is about how long Vyvanse is active. However, everyone is different, so give it a bit more time if you are still feeling the effects. And, most importantly, always ask your doctor if you have questions!
Finally, here are some tips to stay safe on Vyvanse,
With these tips, you can get the most out of your treatment while staying safe.
In the end, it’s all about balance and doing what’s best for your body and mind. Your doctor prescribes certain medications for a reason, so work with them to chart the best course of treatment and how to go about it. In the meantime, if you’re having trouble staying away from alcohol, Reframe is here to help!
1. Can I drink on Vyvanse?
It's generally not recommended to drink alcohol while taking Vyvanse due to potential interactions and increased risk of side effects. Alcohol can amplify Vyvanse's side effects, such as dry mouth, sleep disturbances, increased heart rate, anxiety, appetite suppression, and gastrointestinal issues.
2. Why is mixing Vyvanse and alcohol dangerous?
Mixing Vyvanse, a stimulant, with alcohol, a depressant, can put extra strain on the heart, lead to cardiovascular issues, increase the risk of dependency, impair judgment and decision making, exacerbate ADHD symptoms, and result in risky behaviors.
3. How long after taking Vyvanse can I drink alcohol?
It's best to avoid alcohol completely while taking Vyvanse. However, if you choose to drink, wait at least 14 hours after taking Vyvanse, as that's approximately how long it remains active in the body. Always consult your doctor for personalized advice.
4. How does alcohol affect ADHD symptoms?
Alcohol can worsen ADHD symptoms by impairing focus, attention, and logical thinking. It can also lead to hyperfocusing on immediate stimuli while ignoring important tasks, which contradicts the goals of ADHD management.
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