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Alcohol and Medications

What Happens If You Mix Gabapentin and Alcohol?

Published:
August 30, 2023
·
17 min read
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Written by
Reframe Content Team
A team of researchers and psychologists who specialize in behavioral health and neuroscience. This group collaborates to produce insightful and evidence-based content.
August 30, 2023
·
17 min read
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Certified recovery coach specialized in helping everyone redefine their relationship with alcohol. His approach in coaching focuses on habit formation and addressing the stress in our lives.
August 30, 2023
·
17 min read
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Recognized by Fortune and Fast Company as a top innovator shaping the future of health and known for his pivotal role in helping individuals change their relationship with alcohol.
August 30, 2023
·
17 min read
Reframe App LogoReframe App Logo
Reframe Content Team
August 30, 2023
·
17 min read

If you've ever taken a peek at the back of your medicine bottles (and who hasn’t?) or skimmed through those leaflets that come with them, you've probably seen the all-too-familiar warning: "Do not consume alcohol while taking this medication." But is that always the whole story? Specifically, what if the medication in question is gabapentin? Let's dive deep into the science to find out what really happens when gabapentin and alcohol share the spotlight in your body.

Gabapentin: A Closer Look

Gabapentin, also known under the brand name Neurontin, first came onto the scene in the early 1990s. Its original mission? To treat seizures in patients with epilepsy. However, over the years, doctors began noticing its potential in other areas:

  • Nerve pain. Particularly useful for people with conditions like shingles or diabetic neuropathy, where the nerve endings become super sensitive and can cause pain.
  • Restless leg syndrome. Those annoying sensations in the legs that make you want to move them constantly? Gabapentin can be a curtain call to those, helping patients get a more peaceful night’s sleep.
  • Off-label uses. Beyond its approved uses, some healthcare providers prescribe gabapentin for conditions like anxiety, migraines, and certain types of chronic pain.

While gabapentin's exact mechanisms are still being studied, it's believed to work by calming down overactive nerve cells in the brain. Think of it as the director that instructs over-excitable actors to tone it down a notch. This calming effect is what helps reduce seizures and relieve nerve pain.

Just like any medicine, gabapentin has its potential side effects:

  • Dizziness, drowsiness, and fatigue often top the list. 
  • Some people also experience swelling in the extremities, headaches, or blurred vision.
  • Some might experience mood changes, anxiety, or even depression.
  • In rarer cases, gabapentin can lead to more severe reactions like a skin rash, difficulty breathing, or an irregular heartbeat.

While gabapentin is not an opioid or a classic "addictive" drug, some people might develop a dependency if taken in large amounts over extended periods. This means stopping it suddenly might lead to withdrawal symptoms such as insomnia, nausea, or sweating. It's crucial to follow the doctor's guidelines and not stop taking the medication abruptly without medical advice.

Double Downers

It’s well known that alcohol can act as a depressant on our central nervous system. It slows things down — our thoughts, speech, and movements can become, well, a bit more sluggish.

Now, imagine mixing a drug like gabapentin — another downer. Here’s the rundown:

  • Sleepiness and drowsiness. Both gabapentin and alcohol are known to cause drowsiness — a combined effect can make basic tasks like driving or operating machinery super risky. Even if you felt fine taking either substance alone, the combo could lead to an unexpected snoozefest at inopportune times.
  • Dizziness and coordination. Feeling steady on your feet? Add these two together, and you might feel like you’ve just stepped off a merry-go-round. This dizzying effect could make you more prone to accidents and falls. Plus, it's not the best look if you're trying to navigate through your day seamlessly.
  • Slowed thinking. Imagine trying to solve a puzzle, but the pieces are moving in slow motion. Gabapentin and alcohol together can create this sensation in the brain, making decision-making and clear thinking more challenging.
  • Enhanced mood changes. Both substances can influence mood. Alone, they might cause minor shifts, but together, you could experience amplified feelings of sadness, anxiety, or even euphoria.
  • Compromised judgment. With the brain operating at a slower pace and mood potentially fluctuating, your judgment could take a hit. Whether it's deciding to send that text or choosing to have another drink, the combo might make you do things you'd think twice about normally.

When you see them listed out, it's clear why the pairing of gabapentin and alcohol can be concerning. While both might seem mild on their own, pairing them up can lead to trouble. Always best to tread carefully and stay informed!

Respiratory Risk

One of the more concerning side effects is the potential for respiratory depression — a fancy term for dangerously slow breathing.

When it comes to our body's primary functions, breathing is right there at the top, for obvious reasons. It's so automatic, that most of the time we don't even think about it. However, certain substances can interfere with this natural process. When you introduce both gabapentin and alcohol into the mix, the stakes get higher. Here's why:

Our brain has a built-in system to regulate breathing. This system ensures that we take in enough oxygen to keep our organs functioning and expel carbon dioxide, a waste product. However, certain substances can slow this process down.

As a central nervous system depressant, alcohol can slow down the systems of the body, including respiratory function. In high amounts, alcohol can significantly reduce the body's urge to breathe and decrease the respiratory rate.

Gabapentin, primarily aimed at calming overactive nerve cells in the brain, can also have an impact on respiratory function. Especially in higher doses or when misused, medical experts warn that gabapentin can depress the central nervous system, including brain's respiratory center.

When you mix gabapentin and alcohol, there's a potential for a compounded respiratory depressant effect. Since each substance is capable of slowing down breathing on its own, together the effect is even more dangerous. This serious effect can manifest as:

  • Shallow breathing. Breaths become more superficial, and less oxygen is taken in with each inhale.
  • Reduced oxygen to the brain. This can lead to confusion, dizziness, and in severe cases, loss of consciousness or brain damage.
  • Risk of respiratory failure. In extreme situations, the combined effect can be so severe that the body fails to breathe adequately or stops breathing altogether.

Certain groups might be at a higher risk when combining these substances, including the elderly, those with existing respiratory conditions, and people who misuse or overdose on either substance.

Increased Side Effects

Mixing substances often leads to an intertwining of their side effects. It's like a duet where each singer has their own notes, but when combined, they create an entirely new sound. For gabapentin and alcohol, this duet can bring out some unpleasant surprises:

  1. Memory problems. Both gabapentin and alcohol can impact memory on their own. When combined, the potential for memory impairment grows. This might manifest as:
    • Short-term memory gaps (forgetting recent events or conversations)
    • Difficulty concentrating (challenges in focusing on tasks or following through on actions)
  2. Gastrointestinal issues. While gabapentin can sometimes lead to stomach upset, alcohol is known to irritate the stomach lining. Their combined effect might increase the risk of:
    • Nausea or vomiting (feeling queasy or actually getting sick)
    • Stomach pain (ranging from mild discomfort to sharp pains)
  3. Mood swings. Both substances have the potential to impact mood. Together, they might cause:
    • Heightened anxiety or depression (unease or sadness might be more pronounced)
    • Irritability (a shorter fuse or getting frustrated more easily)
  4. Visual disturbances. Gabapentin occasionally causes blurred vision. Alcohol, on the other hand, can affect eye movement and focus. Together, they might lead to:
    • Double vision
    • Difficulty tracking movements (challenges in following moving objects with the eyes)
  5. Physical discomfort. The combination might amplify some physical side effects like:
    • Headaches (ranging from mild discomfort to severe migraines
    • Dizziness (feeling off-balance or like the room is spinning)
  6. Risk of overdose. When taken in excess, both gabapentin and alcohol have overdose potential. Together, they can increase this risk due to their compounded depressive effects on the central nervous system. Overdose symptoms might include extreme drowsiness, difficulty breathing, loss of consciousness, and in severe cases, death.

Why It’s Especially Important If You’re Cutting Back on Alcohol

If you're in the journey of cutting back or quitting alcohol, you’re already doing a fantastic thing for your body. But adding gabapentin to the equation can complicate things by amping up alcohol cravings and making it harder to stick to your goals. Plus, your body's tolerance and how it reacts to alcohol could be different, and mixing it with gabapentin can be unpredictable if you do end up drinking after a period of abstinence. Here’s a more detailed look at how gabapentin could complicate your recovery:

  • Rebound Sensitivity. As you cut back on alcohol, your nervous system is in a state of heightened alertness or sensitivity. This is because, over time, it became accustomed to alcohol's depressant effects. Now, without the same levels of alcohol, it's like a tightly wound spring, ready to react more significantly to stimuli—including medications.
  • Changing tolerance levels. Your tolerance to alcohol and possibly other substances, including medications, may shift as you reduce your alcohol intake. What was once a "normal" or "safe" dose of gabapentin when you were drinking regularly may now have a more pronounced effect, increasing the risk of side effects.
  • Withdrawal interactions. Alcohol withdrawal itself can come with a slew of symptoms, from mild (like headaches and irritability) to severe (such as seizures). Gabapentin can influence some of these symptoms, either dampening or exaggerating them. It's essential to be aware of these potential shifts and work with a healthcare provider to adjust dosages if necessary.
  • Emotional and psychological adjustments. Reducing alcohol often means confronting emotions or situations previously numbed by drinking. It’s important to tread carefully when introducing a medication that can affect mood or cognition during this emotionally charged period.
  • Risk of relapse. For some, the side effects of medications, or the simple act of mixing substances, can be triggers leading back to drinking. Being mindful of how gabapentin makes you feel, especially in social situations where alcohol might be present, is essential.

Reducing alcohol is a great step towards optimizing health! To get the most out of it, it's essential to ensure that all other substances, including medications like gabapentin, are used safely and effectively. This means being knowledgeable about potential interactions and being proactive in managing them.

Action Steps To Stay Safe

Now that we understand the science, let’s talk about how to be smart and safe:

  • Knowledge is power. Always read those medicine leaflets. They’re packed with good info on what to avoid when you’re on a specific medication.
  • Chat with your doc. If you’re prescribed gabapentin, be open about your alcohol consumption. Your healthcare provider can give you personalized advice.
  • Gabapentin calendar. Keep track of your dosages and timings. Design a personalized gabapentin calendar or set alerts on your phone to ensure consistent intake. This will help in monitoring its effects and prevent unintentional overuse.
  • Symptom journal. Keep a daily journal noting any side effects or feelings when on gabapentin. Over time, you'll have a clearer picture of how it affects you, making it easier to discuss with your healthcare provider.
  • Medication cross-check. Before introducing any new medication or supplement to your regimen, always check for interactions with gabapentin. Some might amplify the side effects or reduce its efficacy.
  • Alcohol tracker. If you're contemplating alcohol intake, have a dedicated app or log that tracks your drinks. This will not only help you limit consumption but also be a reminder of the potential risks with gabapentin.
  • Share your concerns. Share the specifics of your medication with a trusted friend or family member. They can be a second pair of eyes, ensuring you don't accidentally consume alcohol or observing if you’re exhibiting side effects.
  • Stay updated with research. Gabapentin, like all medications, is regularly researched. Periodically check trusted medical websites or subscribe to newsletters for any updates on its effects, recommended dosages, or potential interactions.
  • Avoid the mix. If in doubt, it's always safer to keep alcohol and gabapentin apart. If you’re cutting back on alcohol, set a clear limit for yourself and stick to it.
  • Listen to your body. If something feels off, it probably is. Seek medical attention if you believe you’re experiencing severe side effects.

A Healthy Future

Navigating the world of medications and their interactions can feel like a maze. But with the right information and a proactive approach, you can ensure your journey is both safe and successful. Remember, every step you take toward understanding and respecting your body's reactions is a step toward a healthier, happier you.

If you've ever taken a peek at the back of your medicine bottles (and who hasn’t?) or skimmed through those leaflets that come with them, you've probably seen the all-too-familiar warning: "Do not consume alcohol while taking this medication." But is that always the whole story? Specifically, what if the medication in question is gabapentin? Let's dive deep into the science to find out what really happens when gabapentin and alcohol share the spotlight in your body.

Gabapentin: A Closer Look

Gabapentin, also known under the brand name Neurontin, first came onto the scene in the early 1990s. Its original mission? To treat seizures in patients with epilepsy. However, over the years, doctors began noticing its potential in other areas:

  • Nerve pain. Particularly useful for people with conditions like shingles or diabetic neuropathy, where the nerve endings become super sensitive and can cause pain.
  • Restless leg syndrome. Those annoying sensations in the legs that make you want to move them constantly? Gabapentin can be a curtain call to those, helping patients get a more peaceful night’s sleep.
  • Off-label uses. Beyond its approved uses, some healthcare providers prescribe gabapentin for conditions like anxiety, migraines, and certain types of chronic pain.

While gabapentin's exact mechanisms are still being studied, it's believed to work by calming down overactive nerve cells in the brain. Think of it as the director that instructs over-excitable actors to tone it down a notch. This calming effect is what helps reduce seizures and relieve nerve pain.

Just like any medicine, gabapentin has its potential side effects:

  • Dizziness, drowsiness, and fatigue often top the list. 
  • Some people also experience swelling in the extremities, headaches, or blurred vision.
  • Some might experience mood changes, anxiety, or even depression.
  • In rarer cases, gabapentin can lead to more severe reactions like a skin rash, difficulty breathing, or an irregular heartbeat.

While gabapentin is not an opioid or a classic "addictive" drug, some people might develop a dependency if taken in large amounts over extended periods. This means stopping it suddenly might lead to withdrawal symptoms such as insomnia, nausea, or sweating. It's crucial to follow the doctor's guidelines and not stop taking the medication abruptly without medical advice.

Double Downers

It’s well known that alcohol can act as a depressant on our central nervous system. It slows things down — our thoughts, speech, and movements can become, well, a bit more sluggish.

Now, imagine mixing a drug like gabapentin — another downer. Here’s the rundown:

  • Sleepiness and drowsiness. Both gabapentin and alcohol are known to cause drowsiness — a combined effect can make basic tasks like driving or operating machinery super risky. Even if you felt fine taking either substance alone, the combo could lead to an unexpected snoozefest at inopportune times.
  • Dizziness and coordination. Feeling steady on your feet? Add these two together, and you might feel like you’ve just stepped off a merry-go-round. This dizzying effect could make you more prone to accidents and falls. Plus, it's not the best look if you're trying to navigate through your day seamlessly.
  • Slowed thinking. Imagine trying to solve a puzzle, but the pieces are moving in slow motion. Gabapentin and alcohol together can create this sensation in the brain, making decision-making and clear thinking more challenging.
  • Enhanced mood changes. Both substances can influence mood. Alone, they might cause minor shifts, but together, you could experience amplified feelings of sadness, anxiety, or even euphoria.
  • Compromised judgment. With the brain operating at a slower pace and mood potentially fluctuating, your judgment could take a hit. Whether it's deciding to send that text or choosing to have another drink, the combo might make you do things you'd think twice about normally.

When you see them listed out, it's clear why the pairing of gabapentin and alcohol can be concerning. While both might seem mild on their own, pairing them up can lead to trouble. Always best to tread carefully and stay informed!

Respiratory Risk

One of the more concerning side effects is the potential for respiratory depression — a fancy term for dangerously slow breathing.

When it comes to our body's primary functions, breathing is right there at the top, for obvious reasons. It's so automatic, that most of the time we don't even think about it. However, certain substances can interfere with this natural process. When you introduce both gabapentin and alcohol into the mix, the stakes get higher. Here's why:

Our brain has a built-in system to regulate breathing. This system ensures that we take in enough oxygen to keep our organs functioning and expel carbon dioxide, a waste product. However, certain substances can slow this process down.

As a central nervous system depressant, alcohol can slow down the systems of the body, including respiratory function. In high amounts, alcohol can significantly reduce the body's urge to breathe and decrease the respiratory rate.

Gabapentin, primarily aimed at calming overactive nerve cells in the brain, can also have an impact on respiratory function. Especially in higher doses or when misused, medical experts warn that gabapentin can depress the central nervous system, including brain's respiratory center.

When you mix gabapentin and alcohol, there's a potential for a compounded respiratory depressant effect. Since each substance is capable of slowing down breathing on its own, together the effect is even more dangerous. This serious effect can manifest as:

  • Shallow breathing. Breaths become more superficial, and less oxygen is taken in with each inhale.
  • Reduced oxygen to the brain. This can lead to confusion, dizziness, and in severe cases, loss of consciousness or brain damage.
  • Risk of respiratory failure. In extreme situations, the combined effect can be so severe that the body fails to breathe adequately or stops breathing altogether.

Certain groups might be at a higher risk when combining these substances, including the elderly, those with existing respiratory conditions, and people who misuse or overdose on either substance.

Increased Side Effects

Mixing substances often leads to an intertwining of their side effects. It's like a duet where each singer has their own notes, but when combined, they create an entirely new sound. For gabapentin and alcohol, this duet can bring out some unpleasant surprises:

  1. Memory problems. Both gabapentin and alcohol can impact memory on their own. When combined, the potential for memory impairment grows. This might manifest as:
    • Short-term memory gaps (forgetting recent events or conversations)
    • Difficulty concentrating (challenges in focusing on tasks or following through on actions)
  2. Gastrointestinal issues. While gabapentin can sometimes lead to stomach upset, alcohol is known to irritate the stomach lining. Their combined effect might increase the risk of:
    • Nausea or vomiting (feeling queasy or actually getting sick)
    • Stomach pain (ranging from mild discomfort to sharp pains)
  3. Mood swings. Both substances have the potential to impact mood. Together, they might cause:
    • Heightened anxiety or depression (unease or sadness might be more pronounced)
    • Irritability (a shorter fuse or getting frustrated more easily)
  4. Visual disturbances. Gabapentin occasionally causes blurred vision. Alcohol, on the other hand, can affect eye movement and focus. Together, they might lead to:
    • Double vision
    • Difficulty tracking movements (challenges in following moving objects with the eyes)
  5. Physical discomfort. The combination might amplify some physical side effects like:
    • Headaches (ranging from mild discomfort to severe migraines
    • Dizziness (feeling off-balance or like the room is spinning)
  6. Risk of overdose. When taken in excess, both gabapentin and alcohol have overdose potential. Together, they can increase this risk due to their compounded depressive effects on the central nervous system. Overdose symptoms might include extreme drowsiness, difficulty breathing, loss of consciousness, and in severe cases, death.

Why It’s Especially Important If You’re Cutting Back on Alcohol

If you're in the journey of cutting back or quitting alcohol, you’re already doing a fantastic thing for your body. But adding gabapentin to the equation can complicate things by amping up alcohol cravings and making it harder to stick to your goals. Plus, your body's tolerance and how it reacts to alcohol could be different, and mixing it with gabapentin can be unpredictable if you do end up drinking after a period of abstinence. Here’s a more detailed look at how gabapentin could complicate your recovery:

  • Rebound Sensitivity. As you cut back on alcohol, your nervous system is in a state of heightened alertness or sensitivity. This is because, over time, it became accustomed to alcohol's depressant effects. Now, without the same levels of alcohol, it's like a tightly wound spring, ready to react more significantly to stimuli—including medications.
  • Changing tolerance levels. Your tolerance to alcohol and possibly other substances, including medications, may shift as you reduce your alcohol intake. What was once a "normal" or "safe" dose of gabapentin when you were drinking regularly may now have a more pronounced effect, increasing the risk of side effects.
  • Withdrawal interactions. Alcohol withdrawal itself can come with a slew of symptoms, from mild (like headaches and irritability) to severe (such as seizures). Gabapentin can influence some of these symptoms, either dampening or exaggerating them. It's essential to be aware of these potential shifts and work with a healthcare provider to adjust dosages if necessary.
  • Emotional and psychological adjustments. Reducing alcohol often means confronting emotions or situations previously numbed by drinking. It’s important to tread carefully when introducing a medication that can affect mood or cognition during this emotionally charged period.
  • Risk of relapse. For some, the side effects of medications, or the simple act of mixing substances, can be triggers leading back to drinking. Being mindful of how gabapentin makes you feel, especially in social situations where alcohol might be present, is essential.

Reducing alcohol is a great step towards optimizing health! To get the most out of it, it's essential to ensure that all other substances, including medications like gabapentin, are used safely and effectively. This means being knowledgeable about potential interactions and being proactive in managing them.

Action Steps To Stay Safe

Now that we understand the science, let’s talk about how to be smart and safe:

  • Knowledge is power. Always read those medicine leaflets. They’re packed with good info on what to avoid when you’re on a specific medication.
  • Chat with your doc. If you’re prescribed gabapentin, be open about your alcohol consumption. Your healthcare provider can give you personalized advice.
  • Gabapentin calendar. Keep track of your dosages and timings. Design a personalized gabapentin calendar or set alerts on your phone to ensure consistent intake. This will help in monitoring its effects and prevent unintentional overuse.
  • Symptom journal. Keep a daily journal noting any side effects or feelings when on gabapentin. Over time, you'll have a clearer picture of how it affects you, making it easier to discuss with your healthcare provider.
  • Medication cross-check. Before introducing any new medication or supplement to your regimen, always check for interactions with gabapentin. Some might amplify the side effects or reduce its efficacy.
  • Alcohol tracker. If you're contemplating alcohol intake, have a dedicated app or log that tracks your drinks. This will not only help you limit consumption but also be a reminder of the potential risks with gabapentin.
  • Share your concerns. Share the specifics of your medication with a trusted friend or family member. They can be a second pair of eyes, ensuring you don't accidentally consume alcohol or observing if you’re exhibiting side effects.
  • Stay updated with research. Gabapentin, like all medications, is regularly researched. Periodically check trusted medical websites or subscribe to newsletters for any updates on its effects, recommended dosages, or potential interactions.
  • Avoid the mix. If in doubt, it's always safer to keep alcohol and gabapentin apart. If you’re cutting back on alcohol, set a clear limit for yourself and stick to it.
  • Listen to your body. If something feels off, it probably is. Seek medical attention if you believe you’re experiencing severe side effects.

A Healthy Future

Navigating the world of medications and their interactions can feel like a maze. But with the right information and a proactive approach, you can ensure your journey is both safe and successful. Remember, every step you take toward understanding and respecting your body's reactions is a step toward a healthier, happier you.

Summary FAQs

1. What is gabapentin primarily used for?

Gabapentin was originally developed to treat seizures in epilepsy patients. However, over time, it's also been used for nerve pain, restless leg syndrome, and even some off-label conditions like anxiety and migraines.

2. Why should I be cautious when mixing gabapentin and alcohol?

Combining the two can amplify their side effects, such as drowsiness, dizziness, mood changes, and even slowed thinking. This can make daily tasks risky and potentially harm your overall well-being.

3. How do gabapentin and alcohol affect my breathing?

Both substances can depress the central nervous system, which includes the brain's respiratory center. Together, they might dangerously reduce respiratory function, leading to shallow breathing or even respiratory failure in extreme cases.

4. Can the combination impact my memory?

Yes, both gabapentin and alcohol can individually impair memory. When combined, the risk for memory gaps and difficulties concentrating can increase.

5. I'm on gabapentin. What should I watch out for if I drink alcohol?

Watch for increased drowsiness, dizziness, mood swings, visual disturbances, and gastrointestinal issues. Always prioritize safety and limit alcohol or avoid it altogether while on gabapentin.

6. Are certain groups more vulnerable to the effects of combining these substances?

Yes, particularly the elderly, those with existing respiratory conditions, and individuals who misuse or overdose on either substance can be at higher risk when combining gabapentin and alcohol.

7. If I've been mixing gabapentin and alcohol and feel unwell, what should I do?

Seek medical attention immediately, especially if experiencing severe symptoms like difficulty breathing or loss of consciousness. Always consult with healthcare professionals about any concerns related to medication and substance use.

Take Care of Your Health and Re-examine Your Relationship With Alcohol With Reframe!

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!

The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.

You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.

Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.

And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).

The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!

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