
Worried you might be trapped by your genes? Dive into an engaging exploration of the genetics influencing Alcohol Use Disorder (AUD)! Our genes may map a potential path — but our choices powerfully influence our journey. Read on for insightful, actionable steps towards a healthier, happier life.
Imagine walking through a dense forest on a treasure hunt, knowing that the path to success is littered with dangerous pitfalls. This adventure parallels the journey of navigating our genes, a complex map that outlines our susceptibilities and strengths.
One possible pitfall is Alcohol Use Disorder (AUD), a condition in which drinking becomes a compulsive, detrimental habit — a hidden trap in our genetic forest.
But is the path to AUD pre-determined by our genes, or can we take an alternate route? If you’ve ever turned to Google wondering whether you have the drinking problem that runs in your family, this might be the article for you.
Science has advanced significantly over the years, providing us with a deeper understanding of Alcohol Use Disorder (AUD) and its genetic underpinnings.
There is no single “alcoholic gene” that accounts for AUD. In fact, studies show that genetics account for about half the risk for AUD, meaning our genes influence our likelihood of developing AUD.
Among the 11 pairs of genes associated with an increased risk of developing AUD, here are some of the most common:
While genetic tests are available, it’s still a developing science — and it cannot guarantee the "catching" or preventing of AUD. Any concerns we have about our genetic risks should be discussed with our healthcare provider.
Family history and our childhood environment play a big role, too. This includes whether the following stressors were a part of our upbringing:
It's important to remember that our genetic makeup is not our destiny — it’s only part of the story. Even if our family history included major stressors, such as those listed above, it doesn’t guarantee we’ll develop AUD. Current stressors, life circumstances, and our everyday choices also play a role.
Our genes don’t dictate our journey. Genes play a part, but so do environmental factors — such as our upbringing, job, stressors, social influences, and coping strategies, to name a few.
Knowing the signs of AUD helps us avoid the hidden pitfalls. They range from less severe symptoms (like repeatedly drinking more than we intend) to severe symptoms (such as feeling unable to cut back on drinking, neglecting personal and professional responsibilities, and experiencing withdrawal symptoms when we’re not under the influence).
Much like spotting a trap in the forest, recognizing these signs is the first step towards choosing a safer path. By acknowledging these symptoms, we can start to navigate around the dangers and make decisions that lead us to healthier destinations.
Now that we understand our path isn't solely dictated by our genes and we can identify the signs of AUD, let's talk about how to steer clear of this pitfall.
Our genes may point us towards a risky path, but it's within our power to choose a safer route.
Alcohol Use Disorder, like a hidden trap, is a real and significant risk — but with knowledge, self-awareness, support, and actionable steps, we can navigate around it.
Remember, the goal isn't to fear the forest but to understand its dangers and equip ourselves with the right tools to navigate through it.
Embrace the journey, knowing that every step we take towards reducing our drinking is a step towards a healthier, happier life.

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app today!
Imagine walking through a dense forest on a treasure hunt, knowing that the path to success is littered with dangerous pitfalls. This adventure parallels the journey of navigating our genes, a complex map that outlines our susceptibilities and strengths.
One possible pitfall is Alcohol Use Disorder (AUD), a condition in which drinking becomes a compulsive, detrimental habit — a hidden trap in our genetic forest.
But is the path to AUD pre-determined by our genes, or can we take an alternate route? If you’ve ever turned to Google wondering whether you have the drinking problem that runs in your family, this might be the article for you.
Science has advanced significantly over the years, providing us with a deeper understanding of Alcohol Use Disorder (AUD) and its genetic underpinnings.
There is no single “alcoholic gene” that accounts for AUD. In fact, studies show that genetics account for about half the risk for AUD, meaning our genes influence our likelihood of developing AUD.
Among the 11 pairs of genes associated with an increased risk of developing AUD, here are some of the most common:
While genetic tests are available, it’s still a developing science — and it cannot guarantee the "catching" or preventing of AUD. Any concerns we have about our genetic risks should be discussed with our healthcare provider.
Family history and our childhood environment play a big role, too. This includes whether the following stressors were a part of our upbringing:
It's important to remember that our genetic makeup is not our destiny — it’s only part of the story. Even if our family history included major stressors, such as those listed above, it doesn’t guarantee we’ll develop AUD. Current stressors, life circumstances, and our everyday choices also play a role.
Our genes don’t dictate our journey. Genes play a part, but so do environmental factors — such as our upbringing, job, stressors, social influences, and coping strategies, to name a few.
Knowing the signs of AUD helps us avoid the hidden pitfalls. They range from less severe symptoms (like repeatedly drinking more than we intend) to severe symptoms (such as feeling unable to cut back on drinking, neglecting personal and professional responsibilities, and experiencing withdrawal symptoms when we’re not under the influence).
Much like spotting a trap in the forest, recognizing these signs is the first step towards choosing a safer path. By acknowledging these symptoms, we can start to navigate around the dangers and make decisions that lead us to healthier destinations.
Now that we understand our path isn't solely dictated by our genes and we can identify the signs of AUD, let's talk about how to steer clear of this pitfall.
Our genes may point us towards a risky path, but it's within our power to choose a safer route.
Alcohol Use Disorder, like a hidden trap, is a real and significant risk — but with knowledge, self-awareness, support, and actionable steps, we can navigate around it.
Remember, the goal isn't to fear the forest but to understand its dangers and equip ourselves with the right tools to navigate through it.
Embrace the journey, knowing that every step we take towards reducing our drinking is a step towards a healthier, happier life.

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app today!

Learn the most common alcohol intolerance symptoms, what causes them, and how to manage reactions for a safer, more comfortable drinking experience.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app today!
Alcohol can be the life of the party. But for some of us, it’s the guest that makes everyone uncomfortable. If a single drink leaves you with a flushed face, an upset stomach, or a racing heart, your body is telling you something isn't right. These reactions can turn a fun night out into a stressful one. You might even wonder, can you be allergic to alcohol? While a true alcohol allergy is rare, these are often classic alcohol intolerance symptoms. Understanding what’s happening is the key to feeling more in control.
This is what being allergic to alcohol feels like. What are some signs you're allergic to alcohol? And can you be sensitive to a particular type — for example, can you be allergic to tequila? Or can you be allergic to whiskey? In this article, we’ll explore the differences between the two — and how to know if either could be impacting you.

In an allergy to alcohol, the immune system mistakenly identifies it as a threat and mounts an aggressive response.
Our body perceives the presence of alcohol as a life-threatening situation, and it sends our immune system into overdrive.
Some of us may be wondering, does being allergic to alcohol the same as having alcohol intolerance? Not quite. Alcohol intolerance can cause a variety of physical symptoms, similar to how a person can start sneezing after a strong spray of perfume. Our bodies can respond to alcohol as an irritant, causing adverse reactions that are often misunderstood.
While our immune system is behind alcohol allergies, alcohol intolerance is caused by a glitch in alcohol metabolism. The liver is at the center of this process, converting alcohol to acetaldehyde — a compound that’s more toxic than alcohol itself, which then gets converted into harmless acetic acid. Occasionally genetic variations lead to an enzyme deficiency that throws a wrench in the process, leading to acetaldehyde buildup. The result? We experience unpleasant symptoms, such as flushing, nausea, and rapid heartbeat after drinking.

Let's clear up a common misunderstanding: the symptoms of alcohol intolerance are not the same as feeling tipsy or drunk. When you have this condition, your body reacts almost immediately after you start drinking. One of the most telling signs is the "alcohol flush syndrome," where your face, neck, and even your chest can become warm and noticeably red. This isn't the gradual buzz that comes with intoxication; it's a swift, physical response from your digestive system signaling that it's struggling to process the alcohol. It's a distinct reaction that happens because your body can't properly break down the toxins in what you're drinking.
This reaction happens because of a specific genetic trait. Your body has an enzyme called ALDH2 that's supposed to help break down alcohol. If you have alcohol intolerance, this enzyme doesn't work as it should, causing a rapid buildup of a toxic compound called acetaldehyde. This is very different from an allergic reaction, which involves your immune system, and it's also distinct from the psychoactive effects of getting drunk. It’s a metabolic issue, plain and simple, and it’s why even a small amount of alcohol can trigger such an uncomfortable response.
Alcohol allergies are extremely rare, but when they occur, they can lead to severe symptoms:
An allergy to alcohol can be life-threatening. If you suspect you have an allergic reaction to alcohol, steer clear of it entirely until you’ve consulted with your healthcare provider.
As for the question of whether you can be allergic to a specific type of alcohol, the answer is yes. It all depends on the exact ingredient that’s causing the allergy — it might not be alcohol at all. For example, some people are allergic to grapes and can’t drink wine, but don’t have the same allergic reaction to alcohol when it comes to other types. And can you be allergic to whiskey or tequila? It’s rare but possible. In the case of whiskey, you might be allergic to specific grains that are used in the fermentation process, while in the case of tequila the culprit might be agave.
There is no cure for an alcohol allergy, so the best way to manage it is to avoid alcohol entirely. Treatment focuses on managing symptoms with antihistamines if accidental exposure occurs — however, doing so on a regular basis isn’t a good idea. And remember — always reach out for medical help if you have any concerns.
Unlike a true allergy, alcohol intolerance is a metabolic disorder, meaning your body can't process alcohol properly. The symptoms are uncomfortable and are your body’s way of telling you something isn’t right. These reactions usually happen soon after you have a drink. Recognizing them is the first step toward understanding your body’s relationship with alcohol and making choices that support your well-being.
One of the most common and visible signs of alcohol intolerance is facial flushing. You might notice your face, neck, or chest turning red and feeling warm shortly after drinking. This happens because blood vessels in your skin dilate in response to the buildup of acetaldehyde, a toxic compound your body creates when it metabolizes alcohol. According to the Mayo Clinic, this distinct blushing is a key symptom of the condition. While it might seem like a minor inconvenience, it's a clear signal that your system is struggling to break down alcohol efficiently.
Feeling dizzy, lightheaded, or even nauseous after just a small amount of alcohol could also point to an intolerance. These symptoms can be linked to a drop in blood pressure. When your body can't process alcohol correctly, it can trigger a reaction that affects your cardiovascular system. The Cleveland Clinic notes that low blood pressure, along with feeling sick to your stomach or vomiting, is a common reaction. It’s easy to mistake this for simply having a low tolerance for alcohol, but it’s actually a specific physiological response to a substance your body can’t handle.
If you have asthma, you might notice your symptoms flare up after drinking alcohol. This isn't a coincidence. For some people, alcohol intolerance can aggravate pre-existing respiratory conditions. The ingredients in alcoholic beverages, such as sulfites or histamine, can act as triggers for asthma attacks. The Mayo Clinic includes worsening asthma as a potential symptom of alcohol intolerance. If you find yourself reaching for your inhaler after a glass of wine or beer, it could be a sign that your body is reacting negatively to something in your drink.
So, what’s happening inside your body to cause these reactions? Alcohol intolerance isn't about willpower or how much you're used to drinking. It's a biological process that you can't control. The primary cause is genetic, specifically related to an enzyme that's supposed to help you digest alcohol. However, sometimes the issue isn't with the alcohol (ethanol) itself but with other ingredients commonly found in alcoholic drinks.
The main culprit behind alcohol intolerance is often a faulty enzyme called aldehyde dehydrogenase 2 (ALDH2). When you drink, your liver first breaks down alcohol into a toxic compound called acetaldehyde. Then, the ALDH2 enzyme is supposed to swoop in and break that down into a harmless substance. But if you have an ALDH2 deficiency, this enzyme doesn't work correctly. As a result, acetaldehyde builds up in your blood, causing those unpleasant symptoms like flushing and nausea. It’s a genetic hiccup in your body’s natural detoxification process.
This ALDH2 deficiency is a genetic trait passed down through families. It's most commonly found in people of East Asian descent, which is why facial flushing after drinking is sometimes referred to as "Asian flush" or "Asian glow." However, it's important to remember that anyone can have this genetic variation. According to the Mayo Clinic, while it's most often seen in people of Asian background, this genetic trait can appear in any ethnicity. If your parents have alcohol intolerance, there's a higher chance you might have it, too.
Sometimes, you might experience a reaction that seems like alcohol intolerance, but the alcohol itself isn't the problem. Alcoholic beverages are complex mixtures containing various ingredients that can trigger symptoms. Things like sulfites, histamine, or even specific grains like wheat or barley could be the real cause of your discomfort. This is why you might react to one type of drink, like red wine, but feel fine after another, like vodka. Pinpointing the exact trigger can help you make more informed choices about what you drink.
Sulfites are preservatives that are commonly added to beer and wine to prevent spoilage and oxidation. While they are generally safe for most people, some individuals are sensitive to them. For these people, consuming sulfites can lead to allergy-like symptoms, including breathing problems (especially in those with asthma), hives, and digestive upset. If you find that you primarily react to wine, sulfites could be the reason.
Histamine is another compound that can cause issues. It's produced during the fermentation process by yeast and bacteria and is found in high amounts in certain alcoholic drinks, particularly aged red wines. Your body naturally produces enzymes to break down histamine, but some people don't produce enough. When histamine builds up, it can cause symptoms like headaches, nasal congestion, skin flushing, and digestive problems, which can easily be mistaken for alcohol intolerance.
Ignoring the signs of alcohol intolerance and continuing to drink can do more than just cause temporary discomfort. It can lead to serious health problems down the road. When your body can't break down acetaldehyde effectively, this toxic compound circulates in your system, causing damage to your cells over time. Listening to your body's warning signals is a key part of mindful drinking and protecting your long-term health.
One of the most significant risks associated with drinking alcohol despite having an ALDH2 deficiency is an increased risk of certain cancers. The buildup of acetaldehyde is known to damage DNA and stop cells from repairing this damage, which can lead to cancerous growth. According to Cedars-Sinai, regularly drinking with this condition is linked to a much higher risk of developing cancers of the esophagus, mouth, and throat. It essentially exposes your body to a known carcinogen every time you drink.
Your liver bears the brunt of processing alcohol, and when it's constantly struggling with a buildup of acetaldehyde, it can lead to significant damage. The Cleveland Clinic warns that people with alcohol intolerance who drink regularly have a higher risk for liver diseases, including cirrhosis, which is severe scarring of the liver. Over time, this strain can also contribute to other health issues, including problems with your heart and digestive system, making it crucial to take symptoms of intolerance seriously.
Armed with this knowledge, we can take steps to handle our unexpected guest or, better yet, not invite them at all. Here are seven actionable steps to reevaluate our relationship with alcohol:
Understanding alcohol intolerance and allergy allows us to consider our relationship with alcohol and take strides towards healthier choices. If you think you have an allergy, speak to your healthcare provider. Most likely, they’ll tell you to cut alcohol out entirely and in any form.
If you suspect you have an alcohol intolerance, your body is sending you clear signals. The next step is to listen and respond thoughtfully. Managing intolerance isn't about finding ways to push through the discomfort; it's about understanding what your body needs and adjusting your habits to support your long-term health. This process starts with getting a clear picture of what’s happening, which means turning to a professional for guidance instead of trying to figure it all out on your own. From there, you can build a strategy that feels right for you.
The first and most important step is to talk to your doctor. They can help you confirm whether you have an intolerance and rule out other potential causes for your symptoms. Your doctor will likely start by asking detailed questions about what happens when you drink alcohol — what you drink, how much, and the specific reactions you experience. To get a more definitive answer, they might perform a simple diagnostic procedure to observe how your skin reacts directly to alcohol.
One common method your doctor might use is the ethanol patch test. It’s a straightforward and quick procedure where a drop of ethanol (pure alcohol) is placed on a gauze pad and taped to your arm. After about seven minutes, the doctor will remove the patch and check the area for a reaction. If your skin becomes red, itchy, or swollen, it’s a strong indicator that you have an alcohol intolerance. This simple test can provide the clarity you need to move forward with a management plan.
It can be tempting to pop an antihistamine or an antacid before a night out to prevent the uncomfortable symptoms of alcohol intolerance. However, this is a risky strategy. Masking your symptoms doesn't address the root issue; it only tricks you into thinking you can handle more alcohol than your body is equipped to process. This can lead you to drink more, putting you at risk for more severe health problems down the line. Your body’s reaction is a warning sign, and covering it up doesn’t make the danger go away.
The most effective way to manage alcohol intolerance is also the simplest: avoid or significantly limit your alcohol intake. When your body reacts with flushing, nausea, or a headache, it’s telling you that alcohol isn't safe for it. Trying to "gut through" the discomfort ignores these crucial signals. Instead, this is an opportunity to practice mindful drinking. Pay close attention to how you feel, honor your body’s limits, and explore the vibrant world of alcohol-free alternatives that won’t leave you feeling unwell.
If you suddenly start experiencing symptoms after drinking, it’s time to schedule a visit with your doctor to figure out the cause. It’s also important to be honest with yourself and your doctor about your drinking patterns. If you find that you continue to drink heavily despite feeling sick every time, it could be a sign of something more serious. A healthcare professional can provide compassionate support and resources to help you change your relationship with alcohol for good.
What's the real difference between an alcohol allergy and an intolerance? Think of it this way: an allergy is your immune system overreacting, treating alcohol like a dangerous invader. This can cause severe reactions like hives, swelling, and difficulty breathing. An intolerance, on the other hand, is a digestive issue. Your body lacks the right enzyme to break down alcohol properly, which leads to uncomfortable symptoms like facial flushing and nausea. While both are unpleasant, an allergy is an immune response, while an intolerance is a metabolic one.
I get a red, flushed face when I drink. Is that a big deal? That red face, often called "alcohol flush," is more than just a cosmetic issue. It's a clear sign that your body is struggling to process alcohol, causing a toxic compound called acetaldehyde to build up in your system. While it might seem harmless, consistently drinking when you have this reaction is linked to serious long-term health risks, including a higher chance of developing certain cancers. It's your body's way of sending a very direct warning signal.
Why do I only react to certain drinks, like red wine, but not others? This is a great question, and it often comes down to the other ingredients in your drink. It might not be the alcohol (ethanol) that's causing your symptoms. Red wine, for example, is high in compounds like sulfites and histamine, which are common triggers for allergy-like reactions in sensitive people. You might be reacting to one of these components rather than the alcohol itself, which explains why you can drink something purer, like vodka, without the same issue.
Is it safe to just take an antihistamine before drinking to stop the reaction? This is a risky approach that I wouldn't recommend. Taking an antihistamine might cover up the outward symptoms like flushing or a stuffy nose, but it does nothing to stop the internal process. Your body is still struggling to break down the alcohol and acetaldehyde is still building up. Masking the symptoms can give you a false sense of security, potentially leading you to drink more than your body can handle and increasing your risk of long-term damage.
I never used to have a problem with alcohol. Can you develop an intolerance later in life? Yes, it's possible to notice symptoms of intolerance suddenly, even if you've been drinking for years without any issues. Sometimes this can be linked to other factors, like developing new health conditions or starting certain medications. If you suddenly start reacting poorly to alcohol, it's a good idea to talk to your doctor. They can help you figure out the underlying cause and give you the best advice for moving forward.
Alcohol can be the life of the party. But for some of us, it’s the guest that makes everyone uncomfortable. If a single drink leaves you with a flushed face, an upset stomach, or a racing heart, your body is telling you something isn't right. These reactions can turn a fun night out into a stressful one. You might even wonder, can you be allergic to alcohol? While a true alcohol allergy is rare, these are often classic alcohol intolerance symptoms. Understanding what’s happening is the key to feeling more in control.
This is what being allergic to alcohol feels like. What are some signs you're allergic to alcohol? And can you be sensitive to a particular type — for example, can you be allergic to tequila? Or can you be allergic to whiskey? In this article, we’ll explore the differences between the two — and how to know if either could be impacting you.

In an allergy to alcohol, the immune system mistakenly identifies it as a threat and mounts an aggressive response.
Our body perceives the presence of alcohol as a life-threatening situation, and it sends our immune system into overdrive.
Some of us may be wondering, does being allergic to alcohol the same as having alcohol intolerance? Not quite. Alcohol intolerance can cause a variety of physical symptoms, similar to how a person can start sneezing after a strong spray of perfume. Our bodies can respond to alcohol as an irritant, causing adverse reactions that are often misunderstood.
While our immune system is behind alcohol allergies, alcohol intolerance is caused by a glitch in alcohol metabolism. The liver is at the center of this process, converting alcohol to acetaldehyde — a compound that’s more toxic than alcohol itself, which then gets converted into harmless acetic acid. Occasionally genetic variations lead to an enzyme deficiency that throws a wrench in the process, leading to acetaldehyde buildup. The result? We experience unpleasant symptoms, such as flushing, nausea, and rapid heartbeat after drinking.

Let's clear up a common misunderstanding: the symptoms of alcohol intolerance are not the same as feeling tipsy or drunk. When you have this condition, your body reacts almost immediately after you start drinking. One of the most telling signs is the "alcohol flush syndrome," where your face, neck, and even your chest can become warm and noticeably red. This isn't the gradual buzz that comes with intoxication; it's a swift, physical response from your digestive system signaling that it's struggling to process the alcohol. It's a distinct reaction that happens because your body can't properly break down the toxins in what you're drinking.
This reaction happens because of a specific genetic trait. Your body has an enzyme called ALDH2 that's supposed to help break down alcohol. If you have alcohol intolerance, this enzyme doesn't work as it should, causing a rapid buildup of a toxic compound called acetaldehyde. This is very different from an allergic reaction, which involves your immune system, and it's also distinct from the psychoactive effects of getting drunk. It’s a metabolic issue, plain and simple, and it’s why even a small amount of alcohol can trigger such an uncomfortable response.
Alcohol allergies are extremely rare, but when they occur, they can lead to severe symptoms:
An allergy to alcohol can be life-threatening. If you suspect you have an allergic reaction to alcohol, steer clear of it entirely until you’ve consulted with your healthcare provider.
As for the question of whether you can be allergic to a specific type of alcohol, the answer is yes. It all depends on the exact ingredient that’s causing the allergy — it might not be alcohol at all. For example, some people are allergic to grapes and can’t drink wine, but don’t have the same allergic reaction to alcohol when it comes to other types. And can you be allergic to whiskey or tequila? It’s rare but possible. In the case of whiskey, you might be allergic to specific grains that are used in the fermentation process, while in the case of tequila the culprit might be agave.
There is no cure for an alcohol allergy, so the best way to manage it is to avoid alcohol entirely. Treatment focuses on managing symptoms with antihistamines if accidental exposure occurs — however, doing so on a regular basis isn’t a good idea. And remember — always reach out for medical help if you have any concerns.
Unlike a true allergy, alcohol intolerance is a metabolic disorder, meaning your body can't process alcohol properly. The symptoms are uncomfortable and are your body’s way of telling you something isn’t right. These reactions usually happen soon after you have a drink. Recognizing them is the first step toward understanding your body’s relationship with alcohol and making choices that support your well-being.
One of the most common and visible signs of alcohol intolerance is facial flushing. You might notice your face, neck, or chest turning red and feeling warm shortly after drinking. This happens because blood vessels in your skin dilate in response to the buildup of acetaldehyde, a toxic compound your body creates when it metabolizes alcohol. According to the Mayo Clinic, this distinct blushing is a key symptom of the condition. While it might seem like a minor inconvenience, it's a clear signal that your system is struggling to break down alcohol efficiently.
Feeling dizzy, lightheaded, or even nauseous after just a small amount of alcohol could also point to an intolerance. These symptoms can be linked to a drop in blood pressure. When your body can't process alcohol correctly, it can trigger a reaction that affects your cardiovascular system. The Cleveland Clinic notes that low blood pressure, along with feeling sick to your stomach or vomiting, is a common reaction. It’s easy to mistake this for simply having a low tolerance for alcohol, but it’s actually a specific physiological response to a substance your body can’t handle.
If you have asthma, you might notice your symptoms flare up after drinking alcohol. This isn't a coincidence. For some people, alcohol intolerance can aggravate pre-existing respiratory conditions. The ingredients in alcoholic beverages, such as sulfites or histamine, can act as triggers for asthma attacks. The Mayo Clinic includes worsening asthma as a potential symptom of alcohol intolerance. If you find yourself reaching for your inhaler after a glass of wine or beer, it could be a sign that your body is reacting negatively to something in your drink.
So, what’s happening inside your body to cause these reactions? Alcohol intolerance isn't about willpower or how much you're used to drinking. It's a biological process that you can't control. The primary cause is genetic, specifically related to an enzyme that's supposed to help you digest alcohol. However, sometimes the issue isn't with the alcohol (ethanol) itself but with other ingredients commonly found in alcoholic drinks.
The main culprit behind alcohol intolerance is often a faulty enzyme called aldehyde dehydrogenase 2 (ALDH2). When you drink, your liver first breaks down alcohol into a toxic compound called acetaldehyde. Then, the ALDH2 enzyme is supposed to swoop in and break that down into a harmless substance. But if you have an ALDH2 deficiency, this enzyme doesn't work correctly. As a result, acetaldehyde builds up in your blood, causing those unpleasant symptoms like flushing and nausea. It’s a genetic hiccup in your body’s natural detoxification process.
This ALDH2 deficiency is a genetic trait passed down through families. It's most commonly found in people of East Asian descent, which is why facial flushing after drinking is sometimes referred to as "Asian flush" or "Asian glow." However, it's important to remember that anyone can have this genetic variation. According to the Mayo Clinic, while it's most often seen in people of Asian background, this genetic trait can appear in any ethnicity. If your parents have alcohol intolerance, there's a higher chance you might have it, too.
Sometimes, you might experience a reaction that seems like alcohol intolerance, but the alcohol itself isn't the problem. Alcoholic beverages are complex mixtures containing various ingredients that can trigger symptoms. Things like sulfites, histamine, or even specific grains like wheat or barley could be the real cause of your discomfort. This is why you might react to one type of drink, like red wine, but feel fine after another, like vodka. Pinpointing the exact trigger can help you make more informed choices about what you drink.
Sulfites are preservatives that are commonly added to beer and wine to prevent spoilage and oxidation. While they are generally safe for most people, some individuals are sensitive to them. For these people, consuming sulfites can lead to allergy-like symptoms, including breathing problems (especially in those with asthma), hives, and digestive upset. If you find that you primarily react to wine, sulfites could be the reason.
Histamine is another compound that can cause issues. It's produced during the fermentation process by yeast and bacteria and is found in high amounts in certain alcoholic drinks, particularly aged red wines. Your body naturally produces enzymes to break down histamine, but some people don't produce enough. When histamine builds up, it can cause symptoms like headaches, nasal congestion, skin flushing, and digestive problems, which can easily be mistaken for alcohol intolerance.
Ignoring the signs of alcohol intolerance and continuing to drink can do more than just cause temporary discomfort. It can lead to serious health problems down the road. When your body can't break down acetaldehyde effectively, this toxic compound circulates in your system, causing damage to your cells over time. Listening to your body's warning signals is a key part of mindful drinking and protecting your long-term health.
One of the most significant risks associated with drinking alcohol despite having an ALDH2 deficiency is an increased risk of certain cancers. The buildup of acetaldehyde is known to damage DNA and stop cells from repairing this damage, which can lead to cancerous growth. According to Cedars-Sinai, regularly drinking with this condition is linked to a much higher risk of developing cancers of the esophagus, mouth, and throat. It essentially exposes your body to a known carcinogen every time you drink.
Your liver bears the brunt of processing alcohol, and when it's constantly struggling with a buildup of acetaldehyde, it can lead to significant damage. The Cleveland Clinic warns that people with alcohol intolerance who drink regularly have a higher risk for liver diseases, including cirrhosis, which is severe scarring of the liver. Over time, this strain can also contribute to other health issues, including problems with your heart and digestive system, making it crucial to take symptoms of intolerance seriously.
Armed with this knowledge, we can take steps to handle our unexpected guest or, better yet, not invite them at all. Here are seven actionable steps to reevaluate our relationship with alcohol:
Understanding alcohol intolerance and allergy allows us to consider our relationship with alcohol and take strides towards healthier choices. If you think you have an allergy, speak to your healthcare provider. Most likely, they’ll tell you to cut alcohol out entirely and in any form.
If you suspect you have an alcohol intolerance, your body is sending you clear signals. The next step is to listen and respond thoughtfully. Managing intolerance isn't about finding ways to push through the discomfort; it's about understanding what your body needs and adjusting your habits to support your long-term health. This process starts with getting a clear picture of what’s happening, which means turning to a professional for guidance instead of trying to figure it all out on your own. From there, you can build a strategy that feels right for you.
The first and most important step is to talk to your doctor. They can help you confirm whether you have an intolerance and rule out other potential causes for your symptoms. Your doctor will likely start by asking detailed questions about what happens when you drink alcohol — what you drink, how much, and the specific reactions you experience. To get a more definitive answer, they might perform a simple diagnostic procedure to observe how your skin reacts directly to alcohol.
One common method your doctor might use is the ethanol patch test. It’s a straightforward and quick procedure where a drop of ethanol (pure alcohol) is placed on a gauze pad and taped to your arm. After about seven minutes, the doctor will remove the patch and check the area for a reaction. If your skin becomes red, itchy, or swollen, it’s a strong indicator that you have an alcohol intolerance. This simple test can provide the clarity you need to move forward with a management plan.
It can be tempting to pop an antihistamine or an antacid before a night out to prevent the uncomfortable symptoms of alcohol intolerance. However, this is a risky strategy. Masking your symptoms doesn't address the root issue; it only tricks you into thinking you can handle more alcohol than your body is equipped to process. This can lead you to drink more, putting you at risk for more severe health problems down the line. Your body’s reaction is a warning sign, and covering it up doesn’t make the danger go away.
The most effective way to manage alcohol intolerance is also the simplest: avoid or significantly limit your alcohol intake. When your body reacts with flushing, nausea, or a headache, it’s telling you that alcohol isn't safe for it. Trying to "gut through" the discomfort ignores these crucial signals. Instead, this is an opportunity to practice mindful drinking. Pay close attention to how you feel, honor your body’s limits, and explore the vibrant world of alcohol-free alternatives that won’t leave you feeling unwell.
If you suddenly start experiencing symptoms after drinking, it’s time to schedule a visit with your doctor to figure out the cause. It’s also important to be honest with yourself and your doctor about your drinking patterns. If you find that you continue to drink heavily despite feeling sick every time, it could be a sign of something more serious. A healthcare professional can provide compassionate support and resources to help you change your relationship with alcohol for good.
What's the real difference between an alcohol allergy and an intolerance? Think of it this way: an allergy is your immune system overreacting, treating alcohol like a dangerous invader. This can cause severe reactions like hives, swelling, and difficulty breathing. An intolerance, on the other hand, is a digestive issue. Your body lacks the right enzyme to break down alcohol properly, which leads to uncomfortable symptoms like facial flushing and nausea. While both are unpleasant, an allergy is an immune response, while an intolerance is a metabolic one.
I get a red, flushed face when I drink. Is that a big deal? That red face, often called "alcohol flush," is more than just a cosmetic issue. It's a clear sign that your body is struggling to process alcohol, causing a toxic compound called acetaldehyde to build up in your system. While it might seem harmless, consistently drinking when you have this reaction is linked to serious long-term health risks, including a higher chance of developing certain cancers. It's your body's way of sending a very direct warning signal.
Why do I only react to certain drinks, like red wine, but not others? This is a great question, and it often comes down to the other ingredients in your drink. It might not be the alcohol (ethanol) that's causing your symptoms. Red wine, for example, is high in compounds like sulfites and histamine, which are common triggers for allergy-like reactions in sensitive people. You might be reacting to one of these components rather than the alcohol itself, which explains why you can drink something purer, like vodka, without the same issue.
Is it safe to just take an antihistamine before drinking to stop the reaction? This is a risky approach that I wouldn't recommend. Taking an antihistamine might cover up the outward symptoms like flushing or a stuffy nose, but it does nothing to stop the internal process. Your body is still struggling to break down the alcohol and acetaldehyde is still building up. Masking the symptoms can give you a false sense of security, potentially leading you to drink more than your body can handle and increasing your risk of long-term damage.
I never used to have a problem with alcohol. Can you develop an intolerance later in life? Yes, it's possible to notice symptoms of intolerance suddenly, even if you've been drinking for years without any issues. Sometimes this can be linked to other factors, like developing new health conditions or starting certain medications. If you suddenly start reacting poorly to alcohol, it's a good idea to talk to your doctor. They can help you figure out the underlying cause and give you the best advice for moving forward.

Have your kidneys ever hurt after a night of heavy drinking? This isn’t uncommon. Explore how alcohol affects our kidneys and what we can do to keep them functioning optimally.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
It always seems to happen: you meet some friends for a happy hour and end up having one drink too many. You go to bed way more tipsy than you would have liked, and when you wake up, you feel like you’ve been hit by a truck. But it’s not just the headache, nausea, and brain fog — it’s a weird pain deep in your abdomen. Is it possible that your kidneys are actually in pain from drinking alcohol?
Does alcohol affect kidneys? What does kidney pain after drinking mean? And can alcohol cause kidney stones? In this post, we’ll explore why our kidneys are so important and how alcohol affects their functioning. We’ll also offer tips for enhancing our kidney health. Let’s get started!

Before we dive into how alcohol affects our kidneys, it’s helpful to look at how our kidneys work and why they’re so important. We don’t often think about them, but these two small organs are as vital to our health as our heart and lungs, performing complex and vital functions that keep the rest of our body in balance.
Shaped like kidney beans (hence the name!), our kidneys are located deep in our abdomen, on either side of our spine. Consider them a filtration system: their main job is to remove waste products and excess fluid from our body.
Here’s how it works: every minute, about one liter of blood — or one-fifth of all the blood pumped by the heart — enters the kidneys through our arteries. This blood is cleaned by passing through millions of tiny blood filters, called nephrons. Any waste materials or excess fluid is passed into the bladder where it is stored as urine, while the newly-filtered blood returns to our bloodstream through our veins.
This process helps keep us alive: without a filtration system, we would poison ourselves with a buildup of toxins and waste. Our kidneys work hard day in and day out to prevent this from happening. In fact, every 24 hours, our kidneys filter and return to the bloodstream about 200 quarts of fluid. Approximately two quarts are eliminated from the body in the form of urine, while the remainder is retained in the body.
In addition to filtering the blood, our kidneys have 3 other important functions:
Interestingly, while most people are born with two kidneys, a person can live a normal and long life with only one healthy kidney. If one kidney is lost, the other kidney can increase its working capacity and provide up to 75% of normal kidney function. This is why people can donate a kidney to someone who needs it.

Now that we know how important and hard working our kidneys are, we can ask the next important question: does alcohol affect kidneys? Simply put: yes! This might not be all that surprising, given that alcohol is a toxin. After all, it’s their job to filter out toxic substances. But let’s take a closer look at 4 specific ways alcohol affects our kidneys:
One significant way alcohol affects our kidneys is by making it more difficult for them to function effectively. For instance, alcohol impairs the structure and function of the nephrons — those functional units of our kidneys responsible for filtering waste products and excess fluids. This can lead to a condition called acute kidney injury, which occurs when the toxins from alcohol build up in our body quickly and our kidneys can’t maintain the right fluid balance. Binge drinking in particular places a great strain on the kidneys and can cause acute kidney damage.
Furthermore, alcohol can affect kidney function by causing or exacerbating other health conditions that harm the kidneys. For example, alcohol is a known risk factor for high blood pressure, a leading cause of kidney damage. Additionally, excessive alcohol consumption can contribute to liver damage and disease, which can, in turn, impair kidney function. Furthermore, alcohol can interfere with the body's ability to regulate fluids and electrolytes, leading to dehydration and electrolyte imbalances that can strain the kidneys.
Finally let’s dispel a myth. Because alcohol is a diuretic, some might think it helps “flush out” the kidneys, but that’s not the case. In fact, it makes them work overtime while depleting the body of important nutrients and damaging the kidneys in the process.
So is beer — an especially potent diuretic — good for your kidneys? The answer is no. Just like other types of alcohol, beer can put unnecessary strain on the kidneys.
It could mean a kidney infection. Alcohol can also increase the risk of kidney infections, which typically start in the bladder and travel up the ureters to the kidneys. Alcohol impairs the immune system, making it more difficult for our body to fight off infections. Additionally, because alcohol can cause dehydration, this can lead to a higher concentration of bacteria in the urinary tract, increasing the risk of a urinary tract infection (UTI). UTIs that spread to the bladder may cause kidney pain and lead to a kidney infection.
Excessive alcohol consumption has been linked to an increased risk of developing chronic kidney disease (CKD), a long-term condition characterized by a gradual loss of kidney function. The likelihood is greater for individuals who already have other risk factors for the disease, such as high blood pressure or diabetes. Smokers who are heavy drinkers have about five times more chance of developing CKD than people who don’t smoke or drink alcohol to excess.
What are the first signs? While the symptoms below can be signs of many different conditions, they are some of the typical ones for CKD:
Alcohol can also interfere with the effectiveness of medications used to manage kidney disease and its complications. For example, alcohol can reduce the effectiveness of blood pressure medications, making it more difficult to control high blood pressure, a leading cause of CKD.
While alcohol consumption isn’t directly linked to kidney stones (hardened deposits formed from minerals and salts in the kidneys), research suggests it can contribute to their development and progression. They can be incredibly painful and sometimes require surgical intervention.
Since alcohol is dehydrating, it increases the concentration of minerals in our urine, which elevates the risk of stone formation. This risk is especially high during instances of binge drinking, which quickly depletes the body's water content. This is also why we might experience kidney pain after a night of heavy drinking.
Alcohol can also affect the balance of acid and alkaline substances in the urine. High levels of uric acid can lead to the formation of uric acid stones. Regular and heavy consumption of alcohol, especially beer and spirits, is associated with higher uric acid levels in the body.
Furthermore, alcohol can exacerbate the symptoms of kidney stones. It can increase the heart rate, leading to faster blood flow and potentially pushing the stones into the ureters, causing severe pain and possible obstruction.
It’s important to be aware of all the ways alcohol can affect our kidneys, as we might develop certain symptoms over time that indicate kidney damage — particularly if we’re consuming alcohol heavily over a long period of time. Plus, issues affecting the kidneys can quickly affect the rest of our body, potentially causing problems in multiple organs.
Watch for these signs that indicate we might have alcohol-related kidney damage:
Kidney pain may be felt in the upper or lower back or between the buttocks and lower ribs. The pain may be felt immediately after consuming alcohol or after we’ve stopped drinking. If we’re experiencing any of the above symptoms or suspect we might have kidney damage from alcohol use, it’s important to contact a medical health professional.
So, how is kidney damage treated — is there a cure? Well, that depends. Acute kidney damage caused by binge drinking will typically resolve itself within a few days. The damage can usually be reversed by stopping drinking and allowing our kidneys to recover. Keep in mind, however, that repeated episodes of binge drinking may cause irreversible damage.
As for chronic kidney disease, sadly there’s no cure. Treatment usually involves helping relieve symptoms and preventing it from getting worse. Our doctor might instruct us to manage our blood pressure levels, follow a kidney-friendly diet, and get adequate exercise.
Depending on the severity of our condition, doctors also might prescribe medications to manage symptoms. In extreme cases, CKD can lead to kidney failure, which may require a kidney transplant or dialysis — a mode of therapy in which a machine is used to perform the job of the kidneys. Untreated, complete kidney failure from alcohol will result in death.
The good news is that we have more control over the health of our kidneys than we might think. It’s worth making certain lifestyle changes, given how vital these organs are to our survival. In addition to limiting our alcohol consumption or eliminating it entirely, there are 5 ways we can keep our kidneys healthy and functioning optimally:
Our kidneys play a vital role in keeping us healthy and alive. They filter out toxins and waste and remove excess fluid from our body. Chronic, long-term alcohol consumption can damage our kidneys, leading to chronic kidney disease or failure. Even a single episode of binge drinking can put stress on our kidneys and cause acute kidney damage. Some of the best things we can do to keep our kidneys healthy include limiting our alcohol consumption, drinking plenty of water, eating a healthy diet, staying physically active, limiting our intake of over-the-counter pain relievers, and not smoking.
If you want to give your kidneys a boost by cutting back on your alcohol consumption, consider trying Reframe. We’re a neuroscience-backed app that has helped millions of people reduce their alcohol consumption and form healthier lifestyle habits.
It always seems to happen: you meet some friends for a happy hour and end up having one drink too many. You go to bed way more tipsy than you would have liked, and when you wake up, you feel like you’ve been hit by a truck. But it’s not just the headache, nausea, and brain fog — it’s a weird pain deep in your abdomen. Is it possible that your kidneys are actually in pain from drinking alcohol?
Does alcohol affect kidneys? What does kidney pain after drinking mean? And can alcohol cause kidney stones? In this post, we’ll explore why our kidneys are so important and how alcohol affects their functioning. We’ll also offer tips for enhancing our kidney health. Let’s get started!

Before we dive into how alcohol affects our kidneys, it’s helpful to look at how our kidneys work and why they’re so important. We don’t often think about them, but these two small organs are as vital to our health as our heart and lungs, performing complex and vital functions that keep the rest of our body in balance.
Shaped like kidney beans (hence the name!), our kidneys are located deep in our abdomen, on either side of our spine. Consider them a filtration system: their main job is to remove waste products and excess fluid from our body.
Here’s how it works: every minute, about one liter of blood — or one-fifth of all the blood pumped by the heart — enters the kidneys through our arteries. This blood is cleaned by passing through millions of tiny blood filters, called nephrons. Any waste materials or excess fluid is passed into the bladder where it is stored as urine, while the newly-filtered blood returns to our bloodstream through our veins.
This process helps keep us alive: without a filtration system, we would poison ourselves with a buildup of toxins and waste. Our kidneys work hard day in and day out to prevent this from happening. In fact, every 24 hours, our kidneys filter and return to the bloodstream about 200 quarts of fluid. Approximately two quarts are eliminated from the body in the form of urine, while the remainder is retained in the body.
In addition to filtering the blood, our kidneys have 3 other important functions:
Interestingly, while most people are born with two kidneys, a person can live a normal and long life with only one healthy kidney. If one kidney is lost, the other kidney can increase its working capacity and provide up to 75% of normal kidney function. This is why people can donate a kidney to someone who needs it.

Now that we know how important and hard working our kidneys are, we can ask the next important question: does alcohol affect kidneys? Simply put: yes! This might not be all that surprising, given that alcohol is a toxin. After all, it’s their job to filter out toxic substances. But let’s take a closer look at 4 specific ways alcohol affects our kidneys:
One significant way alcohol affects our kidneys is by making it more difficult for them to function effectively. For instance, alcohol impairs the structure and function of the nephrons — those functional units of our kidneys responsible for filtering waste products and excess fluids. This can lead to a condition called acute kidney injury, which occurs when the toxins from alcohol build up in our body quickly and our kidneys can’t maintain the right fluid balance. Binge drinking in particular places a great strain on the kidneys and can cause acute kidney damage.
Furthermore, alcohol can affect kidney function by causing or exacerbating other health conditions that harm the kidneys. For example, alcohol is a known risk factor for high blood pressure, a leading cause of kidney damage. Additionally, excessive alcohol consumption can contribute to liver damage and disease, which can, in turn, impair kidney function. Furthermore, alcohol can interfere with the body's ability to regulate fluids and electrolytes, leading to dehydration and electrolyte imbalances that can strain the kidneys.
Finally let’s dispel a myth. Because alcohol is a diuretic, some might think it helps “flush out” the kidneys, but that’s not the case. In fact, it makes them work overtime while depleting the body of important nutrients and damaging the kidneys in the process.
So is beer — an especially potent diuretic — good for your kidneys? The answer is no. Just like other types of alcohol, beer can put unnecessary strain on the kidneys.
It could mean a kidney infection. Alcohol can also increase the risk of kidney infections, which typically start in the bladder and travel up the ureters to the kidneys. Alcohol impairs the immune system, making it more difficult for our body to fight off infections. Additionally, because alcohol can cause dehydration, this can lead to a higher concentration of bacteria in the urinary tract, increasing the risk of a urinary tract infection (UTI). UTIs that spread to the bladder may cause kidney pain and lead to a kidney infection.
Excessive alcohol consumption has been linked to an increased risk of developing chronic kidney disease (CKD), a long-term condition characterized by a gradual loss of kidney function. The likelihood is greater for individuals who already have other risk factors for the disease, such as high blood pressure or diabetes. Smokers who are heavy drinkers have about five times more chance of developing CKD than people who don’t smoke or drink alcohol to excess.
What are the first signs? While the symptoms below can be signs of many different conditions, they are some of the typical ones for CKD:
Alcohol can also interfere with the effectiveness of medications used to manage kidney disease and its complications. For example, alcohol can reduce the effectiveness of blood pressure medications, making it more difficult to control high blood pressure, a leading cause of CKD.
While alcohol consumption isn’t directly linked to kidney stones (hardened deposits formed from minerals and salts in the kidneys), research suggests it can contribute to their development and progression. They can be incredibly painful and sometimes require surgical intervention.
Since alcohol is dehydrating, it increases the concentration of minerals in our urine, which elevates the risk of stone formation. This risk is especially high during instances of binge drinking, which quickly depletes the body's water content. This is also why we might experience kidney pain after a night of heavy drinking.
Alcohol can also affect the balance of acid and alkaline substances in the urine. High levels of uric acid can lead to the formation of uric acid stones. Regular and heavy consumption of alcohol, especially beer and spirits, is associated with higher uric acid levels in the body.
Furthermore, alcohol can exacerbate the symptoms of kidney stones. It can increase the heart rate, leading to faster blood flow and potentially pushing the stones into the ureters, causing severe pain and possible obstruction.
It’s important to be aware of all the ways alcohol can affect our kidneys, as we might develop certain symptoms over time that indicate kidney damage — particularly if we’re consuming alcohol heavily over a long period of time. Plus, issues affecting the kidneys can quickly affect the rest of our body, potentially causing problems in multiple organs.
Watch for these signs that indicate we might have alcohol-related kidney damage:
Kidney pain may be felt in the upper or lower back or between the buttocks and lower ribs. The pain may be felt immediately after consuming alcohol or after we’ve stopped drinking. If we’re experiencing any of the above symptoms or suspect we might have kidney damage from alcohol use, it’s important to contact a medical health professional.
So, how is kidney damage treated — is there a cure? Well, that depends. Acute kidney damage caused by binge drinking will typically resolve itself within a few days. The damage can usually be reversed by stopping drinking and allowing our kidneys to recover. Keep in mind, however, that repeated episodes of binge drinking may cause irreversible damage.
As for chronic kidney disease, sadly there’s no cure. Treatment usually involves helping relieve symptoms and preventing it from getting worse. Our doctor might instruct us to manage our blood pressure levels, follow a kidney-friendly diet, and get adequate exercise.
Depending on the severity of our condition, doctors also might prescribe medications to manage symptoms. In extreme cases, CKD can lead to kidney failure, which may require a kidney transplant or dialysis — a mode of therapy in which a machine is used to perform the job of the kidneys. Untreated, complete kidney failure from alcohol will result in death.
The good news is that we have more control over the health of our kidneys than we might think. It’s worth making certain lifestyle changes, given how vital these organs are to our survival. In addition to limiting our alcohol consumption or eliminating it entirely, there are 5 ways we can keep our kidneys healthy and functioning optimally:
Our kidneys play a vital role in keeping us healthy and alive. They filter out toxins and waste and remove excess fluid from our body. Chronic, long-term alcohol consumption can damage our kidneys, leading to chronic kidney disease or failure. Even a single episode of binge drinking can put stress on our kidneys and cause acute kidney damage. Some of the best things we can do to keep our kidneys healthy include limiting our alcohol consumption, drinking plenty of water, eating a healthy diet, staying physically active, limiting our intake of over-the-counter pain relievers, and not smoking.
If you want to give your kidneys a boost by cutting back on your alcohol consumption, consider trying Reframe. We’re a neuroscience-backed app that has helped millions of people reduce their alcohol consumption and form healthier lifestyle habits.

Does that Pinot jive with your Prednisone? We dive into the science behind this potentially harmful combo and offer practical steps to ensure your health isn't on the line. Ready to make informed choices? We thought so!
You’ve had a rough day at work and, after dinner, you find yourself reaching for a glass of wine, hoping to unwind. But then you remember that you’re currently on Prednisone.
We've probably found ourselves in situations like these, faced with a decision: have a drink, take the medication — or both?
This article explores whether it's safe to mix Prednisone and alcohol and the science behind it.
Prednisone is a corticosteroid medication used to suppress our body's immune system, used for conditions such as arthritis, asthma, and severe allergic reactions.
Let's imagine our immune system as a collection of soldiers. Prednisone acts like a high-ranking officer, ordering these soldiers to stand down, easing our body's inflammatory response.
It's crucial to note that while Prednisone is very effective, it can come with a host of side effects, from mild ones (like insomnia and mood changes) to severe ones (like high blood pressure and weakened immunity).
Now, let's add alcohol to the equation. Drinking alcohol is like adding an unruly group of rebels to our imaginary battlefield. They don't listen to the officer's commands and often cause chaos.
In our bodies, alcohol can exacerbate Prednisone's side effects, causing more harm than good. Alcohol increases gastric acidity, leading to stomach issues like ulcers and stomach bleeding, which Prednisone can also cause.
Simultaneously, both substances can harm the liver, the body's primary detoxification organ.
What’s more, drinking while on a long-term Prednisone regimen could lead to osteoporosis, a disease that leads to the weakening and thinning of our bones. This is because Prednisone lowers our bone mineral density, increasing our risk of fractures.
Alcohol impacts the body’s response to insulin and can lead to insulin resistance. This is also the case for Prednisone and other corticosteroids — which means this combo could lead to an increased risk of developing type 2 diabetes.
Another danger of mixing these two is that it might exacerbate whatever underlying condition is driving us to take Prednisone in the first place.
If we drink that glass of wine after taking our Prednisone, and make this a habit, we might experience a range of immediate and long-term symptoms:
While serious reactions are rare, these increase over time if we drink while on long-term doses of Prednisone.
Notably, our bodies may respond differently to the combination, and the severity of symptoms can vary widely. Therefore, recognizing these symptoms early and seeking medical help is crucial.
We've recognized the potential harm in mixing Prednisone and alcohol. What's next? Here are ways we can safeguard our health:
In conclusion, while that glass of wine after a long day is tempting, the potential risks of combining alcohol and Prednisone far outweigh the momentary relief.

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app today!
You’ve had a rough day at work and, after dinner, you find yourself reaching for a glass of wine, hoping to unwind. But then you remember that you’re currently on Prednisone.
We've probably found ourselves in situations like these, faced with a decision: have a drink, take the medication — or both?
This article explores whether it's safe to mix Prednisone and alcohol and the science behind it.
Prednisone is a corticosteroid medication used to suppress our body's immune system, used for conditions such as arthritis, asthma, and severe allergic reactions.
Let's imagine our immune system as a collection of soldiers. Prednisone acts like a high-ranking officer, ordering these soldiers to stand down, easing our body's inflammatory response.
It's crucial to note that while Prednisone is very effective, it can come with a host of side effects, from mild ones (like insomnia and mood changes) to severe ones (like high blood pressure and weakened immunity).
Now, let's add alcohol to the equation. Drinking alcohol is like adding an unruly group of rebels to our imaginary battlefield. They don't listen to the officer's commands and often cause chaos.
In our bodies, alcohol can exacerbate Prednisone's side effects, causing more harm than good. Alcohol increases gastric acidity, leading to stomach issues like ulcers and stomach bleeding, which Prednisone can also cause.
Simultaneously, both substances can harm the liver, the body's primary detoxification organ.
What’s more, drinking while on a long-term Prednisone regimen could lead to osteoporosis, a disease that leads to the weakening and thinning of our bones. This is because Prednisone lowers our bone mineral density, increasing our risk of fractures.
Alcohol impacts the body’s response to insulin and can lead to insulin resistance. This is also the case for Prednisone and other corticosteroids — which means this combo could lead to an increased risk of developing type 2 diabetes.
Another danger of mixing these two is that it might exacerbate whatever underlying condition is driving us to take Prednisone in the first place.
If we drink that glass of wine after taking our Prednisone, and make this a habit, we might experience a range of immediate and long-term symptoms:
While serious reactions are rare, these increase over time if we drink while on long-term doses of Prednisone.
Notably, our bodies may respond differently to the combination, and the severity of symptoms can vary widely. Therefore, recognizing these symptoms early and seeking medical help is crucial.
We've recognized the potential harm in mixing Prednisone and alcohol. What's next? Here are ways we can safeguard our health:
In conclusion, while that glass of wine after a long day is tempting, the potential risks of combining alcohol and Prednisone far outweigh the momentary relief.

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app today!

Alcohol and the digestive system have a complicated relationship. While alcohol is known to disrupt digestion in a number of ways, there are steps you can take to avoid the problem.
The Reframe app is here for you! Our #1-rated app has already helped hundreds of thousands of folks just like you change their drinking habits and swap them for healthier routines.
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Have you ever found yourself nursing a glass of wine, or sipping on your favorite beer, only to be greeted with an unpleasant sensation in your stomach — an unfriendly ache that has you doubling over, wondering if alcohol was the perpetrator?
Many of us have been there: planning a relaxed, stress-free evening, only to be interrupted by a sharp or dull pain in the stomach. It feels like our bodies are betraying us, right? But, in fact, there is a scientific reason for stomach pain — and understanding it may be the key to keeping our stomachs happy and avoiding this discomfort in the future.

The relationship between alcohol and our digestive system is, well, complicated. We sip our favorite drink, it swirls around in our mouth for a bit, then travels down our esophagus and lands in our stomach, the first stop on a tumultuous ride.
The stomach — equipped with acid and enzymes — is our body's initial processing plant for everything we ingest. Alcohol increases the production of stomach acid, a process termed gastric acid secretion.
Why should we care about a little extra acid? Well, this uptick in stomach acid can irritate the stomach lining, leading to inflammation of the stomach. The extra acid can also back up into the esophagus, causing acid reflux.
The other stomach mischief alcohol can make has to do with our gut microbiome — the community of trillions of bacteria living in our digestive tract, which plays a vital role in our overall health. Alcohol can alter this microbiome, adding to the discomfort we feel when drinking. It can harm beneficial bacteria and allow harmful bacteria to thrive. These shifts in our gut microbiota can lead to digestive discomfort, bloating, and increased gut permeability — leaky gut syndrome — which allows toxins to enter our bloodstream. This microbial mayhem might explain why we sometimes feel off after a night of indulging.
On top of wreaking havoc on our stomach lining and microbiome, alcohol can also impact our intestines' ability to absorb nutrients, a condition known as malabsorption. Studies show that alcohol inhibits the absorption of vital nutrients such as thiamine, folic acid, and zinc, leading to deficiencies that can exacerbate our discomfort and have long-term health consequences.
Over time, the irritation caused by alcohol can lead to alcoholic gastritis — an inflammation of the stomach lining that can be very uncomfortable and painful. Alcoholic gastritis often manifests as a burning pain in our stomach, nausea, and sometimes vomiting — symptoms we've probably blamed on a hangover more than once. To learn more about alcoholic gastritis, check out “Can Alcohol Cause Gastritis?”
When that protective lining sustains too much damage, we can end up with stomach ulcers. Known as peptic ulcers, these are sores that develop in the lining of the stomach. While the most common causes of stomach ulcers are infection with the bacteria Helicobacter pylori and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol is a known risk factor that can exacerbate or contribute to the formation of ulcers.
And finally, there’s Irritable Bowel Syndrome (IBS). Anyone who has experienced it knows it's no walk in the park. The link between IBS and alcohol is complex, but many people with IBS experience worsening symptoms after drinking. Scientists have suggested that alcohol could contribute to IBS by altering gut motility, exacerbating visceral hypersensitivity, and causing gut inflammation. So, that extra glass of wine might be why we're making frequent bathroom trips or struggling with cramps and bloating.

Is there anything we can do to get rid of stomach pain after drinking? Here are some tips to try:
Now that we've discovered the causes of alcohol-induced stomach discomfort, we can better understand why our seemingly innocent drinking can wreak havoc on our insides.
The good news? Our drinking habits are well within our control to change. Understanding how alcohol interacts with our bodies is a critical first step in making more informed choices about our drinking habits. A delicate balancing act of drinking alcohol in moderation and considering both our eating habits and the types of drinks we consume can make a world of difference in avoiding that pesky stomach discomfort, acid reflux, and ulcers.
Moreover, there are some specific tips that can help keep alcohol-related stomach troubles at bay:
Ultimately, our bodies are incredible machines that work constantly to keep us healthy. Sometimes, the discomfort we experience is a signal that we need to make better choices.
Research has shown that even small reductions in alcohol consumption can significantly improve digestive symptoms and overall health. A 2021 study published in Alcohol and Alcoholism found that individuals who reduced their drinking experienced an improvement in gut health and reduction in inflammation markers. How's that for motivation?
We should consider strategies like setting drinking limits, choosing alcohol-free days, or exploring tasty non-alcoholic beverages. Every step we take, no matter how small, brings us closer to improved health and wellness.
Have you ever found yourself nursing a glass of wine, or sipping on your favorite beer, only to be greeted with an unpleasant sensation in your stomach — an unfriendly ache that has you doubling over, wondering if alcohol was the perpetrator?
Many of us have been there: planning a relaxed, stress-free evening, only to be interrupted by a sharp or dull pain in the stomach. It feels like our bodies are betraying us, right? But, in fact, there is a scientific reason for stomach pain — and understanding it may be the key to keeping our stomachs happy and avoiding this discomfort in the future.

The relationship between alcohol and our digestive system is, well, complicated. We sip our favorite drink, it swirls around in our mouth for a bit, then travels down our esophagus and lands in our stomach, the first stop on a tumultuous ride.
The stomach — equipped with acid and enzymes — is our body's initial processing plant for everything we ingest. Alcohol increases the production of stomach acid, a process termed gastric acid secretion.
Why should we care about a little extra acid? Well, this uptick in stomach acid can irritate the stomach lining, leading to inflammation of the stomach. The extra acid can also back up into the esophagus, causing acid reflux.
The other stomach mischief alcohol can make has to do with our gut microbiome — the community of trillions of bacteria living in our digestive tract, which plays a vital role in our overall health. Alcohol can alter this microbiome, adding to the discomfort we feel when drinking. It can harm beneficial bacteria and allow harmful bacteria to thrive. These shifts in our gut microbiota can lead to digestive discomfort, bloating, and increased gut permeability — leaky gut syndrome — which allows toxins to enter our bloodstream. This microbial mayhem might explain why we sometimes feel off after a night of indulging.
On top of wreaking havoc on our stomach lining and microbiome, alcohol can also impact our intestines' ability to absorb nutrients, a condition known as malabsorption. Studies show that alcohol inhibits the absorption of vital nutrients such as thiamine, folic acid, and zinc, leading to deficiencies that can exacerbate our discomfort and have long-term health consequences.
Over time, the irritation caused by alcohol can lead to alcoholic gastritis — an inflammation of the stomach lining that can be very uncomfortable and painful. Alcoholic gastritis often manifests as a burning pain in our stomach, nausea, and sometimes vomiting — symptoms we've probably blamed on a hangover more than once. To learn more about alcoholic gastritis, check out “Can Alcohol Cause Gastritis?”
When that protective lining sustains too much damage, we can end up with stomach ulcers. Known as peptic ulcers, these are sores that develop in the lining of the stomach. While the most common causes of stomach ulcers are infection with the bacteria Helicobacter pylori and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol is a known risk factor that can exacerbate or contribute to the formation of ulcers.
And finally, there’s Irritable Bowel Syndrome (IBS). Anyone who has experienced it knows it's no walk in the park. The link between IBS and alcohol is complex, but many people with IBS experience worsening symptoms after drinking. Scientists have suggested that alcohol could contribute to IBS by altering gut motility, exacerbating visceral hypersensitivity, and causing gut inflammation. So, that extra glass of wine might be why we're making frequent bathroom trips or struggling with cramps and bloating.

Is there anything we can do to get rid of stomach pain after drinking? Here are some tips to try:
Now that we've discovered the causes of alcohol-induced stomach discomfort, we can better understand why our seemingly innocent drinking can wreak havoc on our insides.
The good news? Our drinking habits are well within our control to change. Understanding how alcohol interacts with our bodies is a critical first step in making more informed choices about our drinking habits. A delicate balancing act of drinking alcohol in moderation and considering both our eating habits and the types of drinks we consume can make a world of difference in avoiding that pesky stomach discomfort, acid reflux, and ulcers.
Moreover, there are some specific tips that can help keep alcohol-related stomach troubles at bay:
Ultimately, our bodies are incredible machines that work constantly to keep us healthy. Sometimes, the discomfort we experience is a signal that we need to make better choices.
Research has shown that even small reductions in alcohol consumption can significantly improve digestive symptoms and overall health. A 2021 study published in Alcohol and Alcoholism found that individuals who reduced their drinking experienced an improvement in gut health and reduction in inflammation markers. How's that for motivation?
We should consider strategies like setting drinking limits, choosing alcohol-free days, or exploring tasty non-alcoholic beverages. Every step we take, no matter how small, brings us closer to improved health and wellness.

Drinking when we’re sick can weaken with the immune response and interfere with medications — both factors that can make recovery more difficult.
If you’re ready to take charge of your wellness, the Reframe app is here to help you develop a healthier relationship with alcohol. We're proud to have supported hundreds of thousands of people in dialing down or completely eliminating their alcohol intake. With our practical tools, neuroscience-based courses, coping techniques, and a built-in progress tracker, our leading app equips people just like you to form better habits and lower the risks tied to excessive drinking.
Our daily articles give you a deep dive into the brain science behind alcohol. And to make sure the learning sticks, we follow up with daily activities that reinforce the information from the readings. Moreover, you get access to a wealth of courses covering a multitude of topics designed to guide you towards living your best life.
Our community of global users is always available for a chat on our 24/7 Forum, and we also have daily Zoom check-in calls. Plus, our licensed coaches are ready to give you a helping hand. Our in-app Toolkit comes packed with resources to assist you in tackling the hurdles that come with changing your relationship with alcohol – whether you’re facing cravings, mood fluctuations, or an unsupportive circle of friends.
Why choose Reframe? We're all about science, not stigma. Whether you're simply interested in exploring sobriety, aiming to trim down your drinking, or looking to ditch alcohol entirely, we're here cheering you on, without judgment. We're rooting for you to uncover all the amazing possibilities that come along with reducing or eliminating alcohol consumption.
The best part? You get a 7-day free trial of the Reframe app, so there's really no reason not to try us out. We're certain that you'll unearth a whole new world beyond alcohol, and start flourishing again! Isn't it time you got back to living your best life? We want to help you get there!
We've all heard it, right? That glass of whiskey, wine, or brandy will "kill the germs" and cure whatever ails us. There is even a term for it: the "Hot Toddy Effect." And we can't dismiss the psychological comfort that some of us get from this ritual. But is it bad to drink alcohol when you have a cold? What about drinking beer while sick? Or drinking alcohol while sick in general? Let's see what science has to say.
Sorry to burst your bubble — despite what you might have heard from your nana, research shows that drinking can make it harder to recover from illness. The main reason has to do with the immune system, which can be compromised by alcohol. Not exactly what we want when we're battling a nasty cold or flu, is it?
A 2015 study from Alcohol Research reported that alcohol can disrupt our immune response and lung health. By messing with our body's ability to defend us from infections, it becomes easier for us to get sick in the first place.
Part of the reason has to do with the link between alcohol and inflammation. When we are sick, the immune system triggers an inflammatory response to fight off the infection. However, with frequent alcohol consumption keeping the immune system busy by triggering a state of chronic low-grade inflammation, it’s less able to respond with full force when we want it to.

Another important side of the story has to do with medication. Many of us take medicine when we're sick. Unfortunately, alcohol can interact with a variety of medications — often negatively! — leading to unpleasant or dangerous side effects and reducing the ability of the medication to work its magic.
For instance, combining alcohol with acetaminophen — a common ingredient in over-the-counter cold and flu medicines — can potentially cause liver damage. Mixing alcohol with antibiotics can lead to nasty side effects such as nausea, vomiting, and rapid heartbeat.
So, while a warm Hot Toddy might feel soothing on a sore throat, we need to consider the broader impact on our health, especially if we're on medication.
Now let's talk about hydration. When we're sick, staying hydrated is super important. Water helps flush out toxins and keeps our cells functioning properly. Alcohol, however, is a diuretic. It encourages our body to lose more fluid than we take in, which can lead to dehydration.
Dehydration can exacerbate many illness symptoms, like headache and fatigue. So, drinking alcohol when we're sick could potentially make us feel worse. Not really the result we're after, is it?
But what about moderate drinking? Contrary to popular belief, recent studies have shown that when it comes down to it, no level of alcohol is completely safe. Even moderate drinking increases our overall risk of various health issues — so it’s important to weigh the potential benefits against the risks.
So, is it bad to drink alcohol when we’re sick? All in all, it seems the cons significantly outweigh any pros. Our goal should always be to support our bodies, and alcohol when sick might not be our best ally.
We can still enjoy the coziness of a soothing drink, while also giving our bodies the best chance to bounce back. There are plenty of other comforting, warming drinks to enjoy that won't potentially hinder our recovery. So, next time we're feeling under the weather, let's reach for a mug of hot tea or a bowl of nourishing soup instead of that glass of wine or whiskey.
We've all heard it, right? That glass of whiskey, wine, or brandy will "kill the germs" and cure whatever ails us. There is even a term for it: the "Hot Toddy Effect." And we can't dismiss the psychological comfort that some of us get from this ritual. But is it bad to drink alcohol when you have a cold? What about drinking beer while sick? Or drinking alcohol while sick in general? Let's see what science has to say.
Sorry to burst your bubble — despite what you might have heard from your nana, research shows that drinking can make it harder to recover from illness. The main reason has to do with the immune system, which can be compromised by alcohol. Not exactly what we want when we're battling a nasty cold or flu, is it?
A 2015 study from Alcohol Research reported that alcohol can disrupt our immune response and lung health. By messing with our body's ability to defend us from infections, it becomes easier for us to get sick in the first place.
Part of the reason has to do with the link between alcohol and inflammation. When we are sick, the immune system triggers an inflammatory response to fight off the infection. However, with frequent alcohol consumption keeping the immune system busy by triggering a state of chronic low-grade inflammation, it’s less able to respond with full force when we want it to.

Another important side of the story has to do with medication. Many of us take medicine when we're sick. Unfortunately, alcohol can interact with a variety of medications — often negatively! — leading to unpleasant or dangerous side effects and reducing the ability of the medication to work its magic.
For instance, combining alcohol with acetaminophen — a common ingredient in over-the-counter cold and flu medicines — can potentially cause liver damage. Mixing alcohol with antibiotics can lead to nasty side effects such as nausea, vomiting, and rapid heartbeat.
So, while a warm Hot Toddy might feel soothing on a sore throat, we need to consider the broader impact on our health, especially if we're on medication.
Now let's talk about hydration. When we're sick, staying hydrated is super important. Water helps flush out toxins and keeps our cells functioning properly. Alcohol, however, is a diuretic. It encourages our body to lose more fluid than we take in, which can lead to dehydration.
Dehydration can exacerbate many illness symptoms, like headache and fatigue. So, drinking alcohol when we're sick could potentially make us feel worse. Not really the result we're after, is it?
But what about moderate drinking? Contrary to popular belief, recent studies have shown that when it comes down to it, no level of alcohol is completely safe. Even moderate drinking increases our overall risk of various health issues — so it’s important to weigh the potential benefits against the risks.
So, is it bad to drink alcohol when we’re sick? All in all, it seems the cons significantly outweigh any pros. Our goal should always be to support our bodies, and alcohol when sick might not be our best ally.
We can still enjoy the coziness of a soothing drink, while also giving our bodies the best chance to bounce back. There are plenty of other comforting, warming drinks to enjoy that won't potentially hinder our recovery. So, next time we're feeling under the weather, let's reach for a mug of hot tea or a bowl of nourishing soup instead of that glass of wine or whiskey.

Ever notice your allergies are worse after a few drinks? Lift the curtain on seasonal allergies and alcohol — and the combination’s impacts on histamine levels and our immune system.

Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
It’s allergy season and the pollen is everywhere, leaving a light dusting on your car, porch, windowsills and clothes. You wake up sneezing and spend the day blowing your nose, coughing, and trying to soothe a scratchy throat. By the time the evening comes, you’ve had it: you feel like you can barely breathe and can’t get any relief. You go to crack open a bottle of wine with the hope that it will at least help you relax and settle down. But is combining alcohol with allergies a smart move?
In this post, we’ll explore the relationship between allergies and alcohol. We’ll learn how alcohol can worsen allergy symptoms to understand better ways of managing symptoms. Let’s dive in!
Before we look at the relationship between alcohol and allergies, it’s helpful to understand what exactly allergies are and what happens during an allergic reaction.
Simply put, allergies are our immune system’s response to an allergen, such as pollen, bee venom, pet dander, or certain drugs or foods. They occur when our immune system mistakenly identifies these harmless foreign substances as a threat.
When an allergen enters our system, it interacts with specific immune cells called mast cells. These mast cells are armed with receptors that recognize the allergen as an intruder. Once the allergen binds to these receptors, it triggers the mast cells to release a variety of chemicals, including histamines. These histamines cause the classic symptoms we associate with allergies, such as sneezing, watery eyes, itching, congestion, hay fever, or even more severe reactions, depending on the allergy.
The severity of allergies varies from person to person and can range from minor irritation to anaphylaxis, which is a potentially life-threatening energy.
Now that we have a better grasp on allergies, we can turn to the next question: how does alcohol affect our allergy symptoms? Well, the research is pretty clear: studies have found that alcohol can cause or worsen common symptoms of allergies, asthma, and hay fever, such as sneezing, itching, headaches and coughing.
For instance, one study in older people with asthma found that over 40 percent of participants said that drinking alcohol prompted allergy or allergy-like symptoms. And 30-35 percent said it made their asthma worse.
The culprit isn’t necessarily the alcohol itself, but rather what the alcohol contains: histamines. This chemical compound can trigger inflammation and allergic reactions. Histamines occur naturally in varying amounts in almost all food, but are more prevalent in aged or fermented foods or drinks, like alcohol including beer, wine, and liquor. So as soon as we start drinking, our system is flooded with histamine, which can trigger our allergy symptoms.
To complicate matters, alcohol also blocks the production of diamine oxidase (DAO), an enzyme in our body that helps break down histamine. In other words, alcohol not only introduces more histamines into our system, but inhibits the enzyme that our body needs to help break it down. This is ultimately why we might find ourselves sneezing, itching or coughing more after having a drink.
However, when it comes to triggering an allergic reaction, histamines aren’t the only culprit. Sulfites — which is another ingredient found in alcohol, particularly beer and wine — are also to blame and can provoke asthma and other allergy-like symptoms.
Sulfites are used as preservatives in a range of foods and drinks. They’re produced naturally when beer, wine, and cider are made. But manufacturers also use sulfites to increase the shelf life of beers and wines. However, this ingredient has been linked to an increased risk of asthma attacks and allergic reactions. In fact, one study noted that alcohol use triggered an asthma attack in one-third of participants.
Furthermore, many of alcohol’s natural properties can worsen allergy symptoms. For instance, alcohol can cause our blood pressure to go up and down by constricting and dilating our blood vessels. This can worsen allergic reactions. Alcohol is also a diuretic, meaning it increases the amount of water we expel from our body. Dehydration can actually make our allergy symptoms worse.
Even the alcohol manufacturing process can trigger allergic reactions in some people. For instance, drinking alcohol that has been aged in wooden barrels can prompt allergic reactions in people sensitive to tree nuts.
Most alcoholic beverages contain some histamines and sulfites and can thus worsen allergy symptoms. However, some types of alcohol contain more histamines and sulfites than others.
For instance, red wine in particular contains the largest number of histamines, having between 60 to 3,800 micrograms per glass versus white wine, which has between 3 and 120. Most beer also has a lot of histamines, but hard cider and hard liquor—such as vodka and gin—typically have lower amounts.
As for sulfites, beer and red wine tend to have fewer sulfites than white wine. Vodka and gin, however, are usually free of sulfites due to the distillation process.
Another thing to keep in mind is the amount of sugar in alcohol. Since sugar is inflammatory, high sugar content can make allergy symptoms worse. But high sugar content isn’t just limited to mixed drinks: wine can also contain more sugar than we realize. In fact, some mass produced red wines contain as much as 12 grams of residual sugar — meaning the sugar that doesn’t ferment into alcohol — per liter.
Furthermore, depending on our drink of choice, certain ingredients besides alcohol can cause allergy symptoms. For instance, beer usually contains gluten, yeast, and hops. If we’re sensitive to any of these compounds, we might experience allergy-like symptoms after drinking a few beers.
Since our immune system is responsible for protecting us against harmful substances, including allergens, it's helpful to also look at how alcohol affects our immune system.
Multiple studies confirm that alcohol can significantly impair our immune system, potentially leading to heightened allergic responses. Excessive drinking in particular can suppress certain aspects of our immune system, making us more susceptible to allergies and other health issues.
For instance, a recent study found a link between high alcohol use and high IgE levels. IgE is an antibody that the body releases in response to allergens. While this doesn’t mean that alcohol causes allergies, it indicates that alcohol interacts with a component of the body’s allergic response.
Interestingly, non-allergic rhinitis is another condition that mimics allergies but is not triggered by the same immune response as seasonal allergies. Studies have shown that drinking can trigger non-allergic rhinitis symptoms. While the exact mechanisms behind this link are not yet fully understood, it’s an area of ongoing research.
So, what about an allergy to alcohol itself? Is that possible? Our body produces alcohol on its own, so alcohol allergy is actually quite rare. Alcohol intolerance, on the other hand, is much more common. In fact, one study found that 7.2 percent of participants reported experiencing allergy-like symptoms after drinking wine. But only two of the 68 participants had a medically diagnosed allergy.
An alcohol allergy is the result of an immune system problem, while alcohol intolerance is triggered by genetic problems in the digestive system that make it difficult for the body to break down alcohol effectively. For instance, many people with alcohol intolerance have a deficiency in alcohol dehydrogenase (ADH), which is an important enzyme that breaks down alcohol’s toxic compounds. If we suffer from alcohol intolerance, we’ll likely experience facial flushing, nasal congestion, a rash, upset stomach, diarrhea, nausea, or vomiting.
A true alcohol allergy causes far more serious symptoms and may trigger an anaphylactic reaction, which can cause rapid or weak pulse, fainting, shock, coma, and even death.
Given that alcohol can worsen allergy symptoms, it’s probably wise to limit our consumption or avoid it altogether, particularly during an allergy season. Apart from that, here are a few more tips for managing allergy symptoms:
Allergies occur when our immune system mistakenly identifies harmless substances as a threat. This triggers a cascade of symptoms, such as sneezing, watery eyes, coughing, itching, or hay fever. While an actual allergy to alcohol is rare, alcohol has large amounts of histamines, sulfites, and other natural properties which can exacerbate allergy symptoms. If we struggle with allergies, it’s best to limit our consumption of alcohol or eliminate it altogether.
If you want to cut back on your alcohol intake but don’t know where or how to start, consider trying Reframe. We’re a neuroscience-backed app that has helped millions of people reduce their alcohol consumption and enhance their overall health.
It’s allergy season and the pollen is everywhere, leaving a light dusting on your car, porch, windowsills and clothes. You wake up sneezing and spend the day blowing your nose, coughing, and trying to soothe a scratchy throat. By the time the evening comes, you’ve had it: you feel like you can barely breathe and can’t get any relief. You go to crack open a bottle of wine with the hope that it will at least help you relax and settle down. But is combining alcohol with allergies a smart move?
In this post, we’ll explore the relationship between allergies and alcohol. We’ll learn how alcohol can worsen allergy symptoms to understand better ways of managing symptoms. Let’s dive in!
Before we look at the relationship between alcohol and allergies, it’s helpful to understand what exactly allergies are and what happens during an allergic reaction.
Simply put, allergies are our immune system’s response to an allergen, such as pollen, bee venom, pet dander, or certain drugs or foods. They occur when our immune system mistakenly identifies these harmless foreign substances as a threat.
When an allergen enters our system, it interacts with specific immune cells called mast cells. These mast cells are armed with receptors that recognize the allergen as an intruder. Once the allergen binds to these receptors, it triggers the mast cells to release a variety of chemicals, including histamines. These histamines cause the classic symptoms we associate with allergies, such as sneezing, watery eyes, itching, congestion, hay fever, or even more severe reactions, depending on the allergy.
The severity of allergies varies from person to person and can range from minor irritation to anaphylaxis, which is a potentially life-threatening energy.
Now that we have a better grasp on allergies, we can turn to the next question: how does alcohol affect our allergy symptoms? Well, the research is pretty clear: studies have found that alcohol can cause or worsen common symptoms of allergies, asthma, and hay fever, such as sneezing, itching, headaches and coughing.
For instance, one study in older people with asthma found that over 40 percent of participants said that drinking alcohol prompted allergy or allergy-like symptoms. And 30-35 percent said it made their asthma worse.
The culprit isn’t necessarily the alcohol itself, but rather what the alcohol contains: histamines. This chemical compound can trigger inflammation and allergic reactions. Histamines occur naturally in varying amounts in almost all food, but are more prevalent in aged or fermented foods or drinks, like alcohol including beer, wine, and liquor. So as soon as we start drinking, our system is flooded with histamine, which can trigger our allergy symptoms.
To complicate matters, alcohol also blocks the production of diamine oxidase (DAO), an enzyme in our body that helps break down histamine. In other words, alcohol not only introduces more histamines into our system, but inhibits the enzyme that our body needs to help break it down. This is ultimately why we might find ourselves sneezing, itching or coughing more after having a drink.
However, when it comes to triggering an allergic reaction, histamines aren’t the only culprit. Sulfites — which is another ingredient found in alcohol, particularly beer and wine — are also to blame and can provoke asthma and other allergy-like symptoms.
Sulfites are used as preservatives in a range of foods and drinks. They’re produced naturally when beer, wine, and cider are made. But manufacturers also use sulfites to increase the shelf life of beers and wines. However, this ingredient has been linked to an increased risk of asthma attacks and allergic reactions. In fact, one study noted that alcohol use triggered an asthma attack in one-third of participants.
Furthermore, many of alcohol’s natural properties can worsen allergy symptoms. For instance, alcohol can cause our blood pressure to go up and down by constricting and dilating our blood vessels. This can worsen allergic reactions. Alcohol is also a diuretic, meaning it increases the amount of water we expel from our body. Dehydration can actually make our allergy symptoms worse.
Even the alcohol manufacturing process can trigger allergic reactions in some people. For instance, drinking alcohol that has been aged in wooden barrels can prompt allergic reactions in people sensitive to tree nuts.
Most alcoholic beverages contain some histamines and sulfites and can thus worsen allergy symptoms. However, some types of alcohol contain more histamines and sulfites than others.
For instance, red wine in particular contains the largest number of histamines, having between 60 to 3,800 micrograms per glass versus white wine, which has between 3 and 120. Most beer also has a lot of histamines, but hard cider and hard liquor—such as vodka and gin—typically have lower amounts.
As for sulfites, beer and red wine tend to have fewer sulfites than white wine. Vodka and gin, however, are usually free of sulfites due to the distillation process.
Another thing to keep in mind is the amount of sugar in alcohol. Since sugar is inflammatory, high sugar content can make allergy symptoms worse. But high sugar content isn’t just limited to mixed drinks: wine can also contain more sugar than we realize. In fact, some mass produced red wines contain as much as 12 grams of residual sugar — meaning the sugar that doesn’t ferment into alcohol — per liter.
Furthermore, depending on our drink of choice, certain ingredients besides alcohol can cause allergy symptoms. For instance, beer usually contains gluten, yeast, and hops. If we’re sensitive to any of these compounds, we might experience allergy-like symptoms after drinking a few beers.
Since our immune system is responsible for protecting us against harmful substances, including allergens, it's helpful to also look at how alcohol affects our immune system.
Multiple studies confirm that alcohol can significantly impair our immune system, potentially leading to heightened allergic responses. Excessive drinking in particular can suppress certain aspects of our immune system, making us more susceptible to allergies and other health issues.
For instance, a recent study found a link between high alcohol use and high IgE levels. IgE is an antibody that the body releases in response to allergens. While this doesn’t mean that alcohol causes allergies, it indicates that alcohol interacts with a component of the body’s allergic response.
Interestingly, non-allergic rhinitis is another condition that mimics allergies but is not triggered by the same immune response as seasonal allergies. Studies have shown that drinking can trigger non-allergic rhinitis symptoms. While the exact mechanisms behind this link are not yet fully understood, it’s an area of ongoing research.
So, what about an allergy to alcohol itself? Is that possible? Our body produces alcohol on its own, so alcohol allergy is actually quite rare. Alcohol intolerance, on the other hand, is much more common. In fact, one study found that 7.2 percent of participants reported experiencing allergy-like symptoms after drinking wine. But only two of the 68 participants had a medically diagnosed allergy.
An alcohol allergy is the result of an immune system problem, while alcohol intolerance is triggered by genetic problems in the digestive system that make it difficult for the body to break down alcohol effectively. For instance, many people with alcohol intolerance have a deficiency in alcohol dehydrogenase (ADH), which is an important enzyme that breaks down alcohol’s toxic compounds. If we suffer from alcohol intolerance, we’ll likely experience facial flushing, nasal congestion, a rash, upset stomach, diarrhea, nausea, or vomiting.
A true alcohol allergy causes far more serious symptoms and may trigger an anaphylactic reaction, which can cause rapid or weak pulse, fainting, shock, coma, and even death.
Given that alcohol can worsen allergy symptoms, it’s probably wise to limit our consumption or avoid it altogether, particularly during an allergy season. Apart from that, here are a few more tips for managing allergy symptoms:
Allergies occur when our immune system mistakenly identifies harmless substances as a threat. This triggers a cascade of symptoms, such as sneezing, watery eyes, coughing, itching, or hay fever. While an actual allergy to alcohol is rare, alcohol has large amounts of histamines, sulfites, and other natural properties which can exacerbate allergy symptoms. If we struggle with allergies, it’s best to limit our consumption of alcohol or eliminate it altogether.
If you want to cut back on your alcohol intake but don’t know where or how to start, consider trying Reframe. We’re a neuroscience-backed app that has helped millions of people reduce their alcohol consumption and enhance their overall health.

Is drinking alcohol while taking antibiotics really that harmful? Learn why it’s so important not to mix the two — and what types of antibiotics are particularly dangerous.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
We've all been there: feeling under the weather, a visit to the doctor's, and — just like that — a ten-day round of antibiotics. We've probably all been told that mixing alcohol with antibiotics can be dangerous, but is there any truth to this? Is a drink or two really that harmful?
In this post, we’ll explore how alcohol interacts with antibiotics, why it’s never a good idea to mix the two, and what types of antibiotics are particularly dangerous. Let’s dive in!
Antibiotics are medications used to treat bacterial infections like strep throat or a urinary tract infection. To understand what happens when we mix antibiotics and alcohol, we need to first appreciate what antibiotics are doing inside our bodies as they work against harmful bacteria.
Some antibiotics, like penicillin, operate by weakening the bacteria's cell wall, bursting and killing them. Others, such as tetracyclines, block the bacteria's ability to make proteins, their essential building blocks — preventing bacteria from growing and replicating, and allowing our natural defenses to kill them.
When we take an antibiotic, it travels into our stomach and then into our digestive tract. Once in our intestines, they’re absorbed into our bloodstream, battling bacteria wherever in our body they might be.
This is no easy feat. Antibiotics require a lot of energy, resources, and optimal conditions to work effectively. In other words, we need to keep our bodies well hydrated and nourished while taking antibiotics.
When we mix alcohol with antibiotics, things get a little problematic — but not necessarily because the combination impairs antibiotics’ effectiveness. In fact, research indicates that’s not quite the biggest concern. So what’s the problem?
Let’s take a closer look at 3 of the major reasons why we should never mix alcohol with antibiotics:
Mixing alcohol with any type of antibiotic can cause the general side effects mentioned above. However, some antibiotics are particularly dangerous when mixed with alcohol, causing more severe reactions. Let’s take a closer look at 5 specific ways that alcohol interacts with certain antibiotics:
1. Severe side effects. Drinking any amount of alcohol with the medications below can result in severe side effects, such as flushing, headache, nausea and vomiting, and rapid heart rate:
2. Serious heart and abdominal effects. The antibiotics sulfamethoxazole/trimethoprim (Bactrim) and some cephalosporins (like cefoperazone and cefotetan) can lead to serious heart and gastrointestinal (GI) reactions when taken with alcohol, such as severe nausea and vomiting, irregular heart beat, sweating, and high or low blood pressure. Even alcohol-containing products like mouthwash or cough syrups can cause a negative reaction.
3. Dangerously high blood pressure. When mixed with alcohol, a class of drugs known as monoamine oxidase inhibitors (MAOIs) can result in dangerously high blood pressure, possibly leading to a serious event like a heart attack. This includes the antibiotic Linezolid (Zyvox). This is because MAOIs interfere with the breakdown of tyramine, a substance found in fermented foods and in drinks like red wine, sherry, and beer. As a result, tyramine builds up in our body, spiking our heart rate and raising our blood pressure.
4. Severe liver damage. On their own, the antibiotics isoniazid (Hydra) and ketoconazole can cause liver damage and even liver failure. As alcohol negatively affects our liver, we risk severe liver damage by combining either of them with alcohol.
5. Reduced effectiveness. Drinking alcohol while taking doxycycline (Vibramycin-D, Efracea, Periostat) and erythromycin (Pediazole) can decrease their effectiveness. Alcohol hinders our body’s ability to appropriately absorb these antibiotics, decreasing their effectiveness in curing an infection. This can lead to the infection worsening or recurring.
While it’s best to avoid alcohol while taking any antibiotic, it’s especially vital if we’re prescribed the ones mentioned above, given the serious reactions that can occur.
Keep in mind that we should always consult a medical professional to discuss whether it’s safe to consume alcohol while taking any prescription medication, including antibiotics. Here are 3 questions we can consider asking:

So if it’s not a good idea to drink while taking antibiotics, how soon can we start drinking after finishing them? It might be tempting to assume we can start drinking the day after finishing our last dose, but that’s not always the case. Just as it takes time for alcohol to process out of our system, antibiotics also need time to fully clear from our body. It’s typically recommended to avoid consuming alcohol for at least 48 to 72 hours after finishing our last dose.
This is especially important for certain antibiotics. For instance, doctors recommend not drinking alcohol for a full 3 days after taking metronidazole, tinidazole or benznidazole, and cefotetan. This is because alcohol can continue to react with these antibiotics, causing severe side effects, such as nausea, flushing, and a rapid heart rate.
Antibiotics typically come with warning labels and directions, but it’s always important to consult our doctor to determine when it’s safe for us to consume alcohol after taking any type of antibiotic or prescription medication.
Now, let’s say that you made a mistake: you weren’t thinking and took a sip of wine by accident while taking an antibiotic — what should you do? First and foremost, don’t drink any more! But it’s also important to be aware of any signs that indicate you might need medical attention. Here are 6 symptoms to look out for:
Be sure to contact a medical professional if you start experiencing any of these symptoms. Even without alcohol, antibiotics are powerful drugs, so it’s important to be aware of any abnormal changes to our health when taking them.
As we’ve learned, even without adding alcohol into the mix, antibiotics can cause uncomfortable side effects, such as nausea, diarrhea, and abdominal pain. Eating the right foods can help combat these side effects and encourage healing from an infection. Here are 5 types of foods to focus on while taking and after taking antibiotics:
Keep in mind that adequate sleep, hydration, and stress management are equally important for helping to fight off an infection. In addition to alcohol, some research suggests that grapefruits and grapefruit juice can stop the body from breaking down and correctly absorbing antibiotics. Other research indicates that foods fortified with high doses of calcium (such as orange juice) can interfere with the absorption of certain antibiotics.
Finally, always be sure to take your antibiotic as directed. Even if you start to feel better after a couple days, make sure to finish your prescription. This is important for preventing antibiotic resistance, which occurs when bacteria evolve to outsmart the antibiotics designed to kill them.
Mixing alcohol with antibiotics is unwise. Doing so can cause severe side effects and impair our body’s ability to fight an infection and heal. While some antibiotics are more dangerous to mix with alcohol than others, it’s best practice to avoid alcohol while taking any antibiotic. Even after we finish the prescription, we should wait to consume alcohol for at least 48 to 72 hours in order to ensure it’s fully out of our system.
If you want to cut back on your alcohol consumption, consider trying Reframe. We’re a neuroscience-backed app that has helped millions of people reduce their alcohol consumption, boost their health, and enhance their well-being.
We've all been there: feeling under the weather, a visit to the doctor's, and — just like that — a ten-day round of antibiotics. We've probably all been told that mixing alcohol with antibiotics can be dangerous, but is there any truth to this? Is a drink or two really that harmful?
In this post, we’ll explore how alcohol interacts with antibiotics, why it’s never a good idea to mix the two, and what types of antibiotics are particularly dangerous. Let’s dive in!
Antibiotics are medications used to treat bacterial infections like strep throat or a urinary tract infection. To understand what happens when we mix antibiotics and alcohol, we need to first appreciate what antibiotics are doing inside our bodies as they work against harmful bacteria.
Some antibiotics, like penicillin, operate by weakening the bacteria's cell wall, bursting and killing them. Others, such as tetracyclines, block the bacteria's ability to make proteins, their essential building blocks — preventing bacteria from growing and replicating, and allowing our natural defenses to kill them.
When we take an antibiotic, it travels into our stomach and then into our digestive tract. Once in our intestines, they’re absorbed into our bloodstream, battling bacteria wherever in our body they might be.
This is no easy feat. Antibiotics require a lot of energy, resources, and optimal conditions to work effectively. In other words, we need to keep our bodies well hydrated and nourished while taking antibiotics.
When we mix alcohol with antibiotics, things get a little problematic — but not necessarily because the combination impairs antibiotics’ effectiveness. In fact, research indicates that’s not quite the biggest concern. So what’s the problem?
Let’s take a closer look at 3 of the major reasons why we should never mix alcohol with antibiotics:
Mixing alcohol with any type of antibiotic can cause the general side effects mentioned above. However, some antibiotics are particularly dangerous when mixed with alcohol, causing more severe reactions. Let’s take a closer look at 5 specific ways that alcohol interacts with certain antibiotics:
1. Severe side effects. Drinking any amount of alcohol with the medications below can result in severe side effects, such as flushing, headache, nausea and vomiting, and rapid heart rate:
2. Serious heart and abdominal effects. The antibiotics sulfamethoxazole/trimethoprim (Bactrim) and some cephalosporins (like cefoperazone and cefotetan) can lead to serious heart and gastrointestinal (GI) reactions when taken with alcohol, such as severe nausea and vomiting, irregular heart beat, sweating, and high or low blood pressure. Even alcohol-containing products like mouthwash or cough syrups can cause a negative reaction.
3. Dangerously high blood pressure. When mixed with alcohol, a class of drugs known as monoamine oxidase inhibitors (MAOIs) can result in dangerously high blood pressure, possibly leading to a serious event like a heart attack. This includes the antibiotic Linezolid (Zyvox). This is because MAOIs interfere with the breakdown of tyramine, a substance found in fermented foods and in drinks like red wine, sherry, and beer. As a result, tyramine builds up in our body, spiking our heart rate and raising our blood pressure.
4. Severe liver damage. On their own, the antibiotics isoniazid (Hydra) and ketoconazole can cause liver damage and even liver failure. As alcohol negatively affects our liver, we risk severe liver damage by combining either of them with alcohol.
5. Reduced effectiveness. Drinking alcohol while taking doxycycline (Vibramycin-D, Efracea, Periostat) and erythromycin (Pediazole) can decrease their effectiveness. Alcohol hinders our body’s ability to appropriately absorb these antibiotics, decreasing their effectiveness in curing an infection. This can lead to the infection worsening or recurring.
While it’s best to avoid alcohol while taking any antibiotic, it’s especially vital if we’re prescribed the ones mentioned above, given the serious reactions that can occur.
Keep in mind that we should always consult a medical professional to discuss whether it’s safe to consume alcohol while taking any prescription medication, including antibiotics. Here are 3 questions we can consider asking:

So if it’s not a good idea to drink while taking antibiotics, how soon can we start drinking after finishing them? It might be tempting to assume we can start drinking the day after finishing our last dose, but that’s not always the case. Just as it takes time for alcohol to process out of our system, antibiotics also need time to fully clear from our body. It’s typically recommended to avoid consuming alcohol for at least 48 to 72 hours after finishing our last dose.
This is especially important for certain antibiotics. For instance, doctors recommend not drinking alcohol for a full 3 days after taking metronidazole, tinidazole or benznidazole, and cefotetan. This is because alcohol can continue to react with these antibiotics, causing severe side effects, such as nausea, flushing, and a rapid heart rate.
Antibiotics typically come with warning labels and directions, but it’s always important to consult our doctor to determine when it’s safe for us to consume alcohol after taking any type of antibiotic or prescription medication.
Now, let’s say that you made a mistake: you weren’t thinking and took a sip of wine by accident while taking an antibiotic — what should you do? First and foremost, don’t drink any more! But it’s also important to be aware of any signs that indicate you might need medical attention. Here are 6 symptoms to look out for:
Be sure to contact a medical professional if you start experiencing any of these symptoms. Even without alcohol, antibiotics are powerful drugs, so it’s important to be aware of any abnormal changes to our health when taking them.
As we’ve learned, even without adding alcohol into the mix, antibiotics can cause uncomfortable side effects, such as nausea, diarrhea, and abdominal pain. Eating the right foods can help combat these side effects and encourage healing from an infection. Here are 5 types of foods to focus on while taking and after taking antibiotics:
Keep in mind that adequate sleep, hydration, and stress management are equally important for helping to fight off an infection. In addition to alcohol, some research suggests that grapefruits and grapefruit juice can stop the body from breaking down and correctly absorbing antibiotics. Other research indicates that foods fortified with high doses of calcium (such as orange juice) can interfere with the absorption of certain antibiotics.
Finally, always be sure to take your antibiotic as directed. Even if you start to feel better after a couple days, make sure to finish your prescription. This is important for preventing antibiotic resistance, which occurs when bacteria evolve to outsmart the antibiotics designed to kill them.
Mixing alcohol with antibiotics is unwise. Doing so can cause severe side effects and impair our body’s ability to fight an infection and heal. While some antibiotics are more dangerous to mix with alcohol than others, it’s best practice to avoid alcohol while taking any antibiotic. Even after we finish the prescription, we should wait to consume alcohol for at least 48 to 72 hours in order to ensure it’s fully out of our system.
If you want to cut back on your alcohol consumption, consider trying Reframe. We’re a neuroscience-backed app that has helped millions of people reduce their alcohol consumption, boost their health, and enhance their well-being.

Alcohol consumption — even in moderation — is linked to an increased risk of seven types of cancer: those of the breast, liver, mouth and throat, esophagus, colon and rectum, stomach, and pancreas. By understanding these risks and being proactive, we can significantly reduce our risk and prioritize our health.
Although it isn’t a treatment for alcohol use disorder (AUD), the Reframe app can help you cut back on drinking gradually, with the science-backed knowledge to empower you 100% of the way. Our proven program has helped millions of people around the world drink less and live more. And we want to help you get there, too!
The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge.
You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings. Receive encouragement from people worldwide who know exactly what you’re going through! You’ll also have the opportunity to connect with our licensed Reframe coaches for more personalized guidance.
Plus, we’re always introducing new features to optimize your in-app experience. We recently launched our in-app chatbot, Melody, powered by the world’s most powerful AI technology. Melody is here to help as you adjust to a life with less (or no) alcohol.
And that’s not all! Every month, we launch fun challenges, like Dry/Damp January, Mental Health May, and Outdoorsy June. You won’t want to miss out on the chance to participate alongside fellow Reframers (or solo if that’s more your thing!).
The Reframe app is free for 7 days, so you don’t have anything to lose by trying it. Are you ready to feel empowered and discover life beyond alcohol? Then download our app through the App Store or Google Play today!
Cancer is scary — we don’t really like to think about it. And yet, each time we raise a glass for a toast, unwind with a frosty beer after a long day, or complement our meals with a smooth glass of wine, we might inadvertently be playing a dangerous game with our health.
Research shows that even moderate alcohol use can increase our risk of various types of cancer. These claims might sound somewhat shocking, but they’re backed by solid scientific evidence — and this isn't a game of chance we want to play. So, let's delve into seven types of cancer that have been scientifically linked to alcohol consumption.

Did you know that every drink we have daily can raise our risk of breast cancer by 7-10%? This is because alcohol can increase estrogen levels in the body. While essential for many bodily functions, estrogen is a hormone that can stimulate the growth of some types of breast cancer cells.
Liver cancer is one of the most common types of cancer types worldwide, and alcohol has a big part to play here. The liver is a marvel of multitasking: it's involved in various essential functions, such as breaking down harmful substances — including alcohol — from our blood and converting food into energy. Unfortunately, when alcohol enters the scene, it can disrupt these operations, which can eventually lead to serious health problems, including liver cancer.
When we drink alcohol, our liver works to break it down into different chemicals, one of which is acetaldehyde — a known carcinogen. Our bodies do have ways to neutralize and eliminate acetaldehyde, but when we drink to excess, it can build up and damage our liver cells, increasing the likelihood of abnormal cell growth.
The problem doesn’t end there, though. Excessive drinking over a long time can lead to alcoholic liver disease, aka cirrhosis, in which healthy liver tissue is replaced with scar tissue — and eventually liver cancer. This progression isn't immediate, but every drink takes us another step closer.
When we take a sip of alcohol, our mouth and throat are the first in line. Over time, alcohol can damage cells in these areas and trigger changes that might lead to mouth and throat cancer. And if we smoke while drinking, the risk becomes even higher.
Moreover, alcohol consumption can lead to deficiencies of a type of B-vitamin known as folate — a risk factor for mouth and throat cancer.
Alcohol can also lead to esophageal cancer. As we swallow our drink, alcohol comes into direct contact with the esophagus. This contact can lead to irritation and inflammation, causing damage to the esophageal cells. With frequent alcohol exposure, the body’s repair processes can go awry, causing DNA changes in the esophageal cells and potentially leading to esophageal cancer.
One type of esophageal cancer, esophageal squamous cell carcinoma, has been strongly linked to alcohol consumption. The risk is particularly high if we consume large amounts of alcohol over many years. This risk is amplified dramatically if we combine drinking with smoking, creating a potent cocktail of irritants for our esophagus.
Moreover, alcohol makes our esophagus more vulnerable to the damaging effects of acid reflux — a significant risk factor for another type of esophageal cancer called adenocarcinoma.
Our stomachs are not exempt from alcohol's reach either. The stomach is our body's food processor — it breaks down what we eat and drink, preparing it to be used for energy. However, alcohol can disrupt the stomach's protective lining, making it more susceptible to the harmful effects of its own digestive juices. This can lead to ulcers and gastritis, an inflammation of the stomach lining. Both conditions increase the risk of stomach cancer over time.
Moreover, alcohol can act as a solvent, helping other harmful chemicals — such as those from tobacco smoke or certain foods — penetrate the stomach lining, further increasing the risk.
Chronic heavy drinking also affects the stomach’s balance of acids and enzymes, disrupting digestion and leading to malnutrition. At the same time, alcohol's diuretic effect can lead to dehydration, which slows the removal of harmful substances from the stomach, prolonging their contact with the stomach lining.
Alcohol's journey through our bodies doesn't end at the throat or stomach. It also impacts our colon and rectum, where it can increase the risk of colorectal cancer. Studies suggest that alcohol's carcinogenic byproducts, including acetaldehyde, can damage DNA and proteins in our colon and rectum, leading to abnormal cell growth and, potentially, cancer.
Finally, we come to pancreatic cancer. The pancreas is a vital organ in our body with two primary roles: aiding digestion and regulating blood sugar. Despite not being as direct or common as with some other cancers, the link between alcohol and pancreatic cancer is worth looking into.
With chronic alcohol consumption, the pancreas can become inflamed, a condition known as pancreatitis. While acute pancreatitis is usually a short-term illness, it can become chronic with continued drinking. Over time, the constant inflammation and damage can cause DNA changes that lead to abnormal cell growth and, potentially, to cancer.

That's some heavy stuff, right? But here's the silver lining: we have the power to lower our risk with these simple, concrete steps:
The important thing is, every step we take towards reducing our alcohol intake is a victory. It's not about doing it perfectly—it's about making progress.
Cancer is scary — we don’t really like to think about it. And yet, each time we raise a glass for a toast, unwind with a frosty beer after a long day, or complement our meals with a smooth glass of wine, we might inadvertently be playing a dangerous game with our health.
Research shows that even moderate alcohol use can increase our risk of various types of cancer. These claims might sound somewhat shocking, but they’re backed by solid scientific evidence — and this isn't a game of chance we want to play. So, let's delve into seven types of cancer that have been scientifically linked to alcohol consumption.

Did you know that every drink we have daily can raise our risk of breast cancer by 7-10%? This is because alcohol can increase estrogen levels in the body. While essential for many bodily functions, estrogen is a hormone that can stimulate the growth of some types of breast cancer cells.
Liver cancer is one of the most common types of cancer types worldwide, and alcohol has a big part to play here. The liver is a marvel of multitasking: it's involved in various essential functions, such as breaking down harmful substances — including alcohol — from our blood and converting food into energy. Unfortunately, when alcohol enters the scene, it can disrupt these operations, which can eventually lead to serious health problems, including liver cancer.
When we drink alcohol, our liver works to break it down into different chemicals, one of which is acetaldehyde — a known carcinogen. Our bodies do have ways to neutralize and eliminate acetaldehyde, but when we drink to excess, it can build up and damage our liver cells, increasing the likelihood of abnormal cell growth.
The problem doesn’t end there, though. Excessive drinking over a long time can lead to alcoholic liver disease, aka cirrhosis, in which healthy liver tissue is replaced with scar tissue — and eventually liver cancer. This progression isn't immediate, but every drink takes us another step closer.
When we take a sip of alcohol, our mouth and throat are the first in line. Over time, alcohol can damage cells in these areas and trigger changes that might lead to mouth and throat cancer. And if we smoke while drinking, the risk becomes even higher.
Moreover, alcohol consumption can lead to deficiencies of a type of B-vitamin known as folate — a risk factor for mouth and throat cancer.
Alcohol can also lead to esophageal cancer. As we swallow our drink, alcohol comes into direct contact with the esophagus. This contact can lead to irritation and inflammation, causing damage to the esophageal cells. With frequent alcohol exposure, the body’s repair processes can go awry, causing DNA changes in the esophageal cells and potentially leading to esophageal cancer.
One type of esophageal cancer, esophageal squamous cell carcinoma, has been strongly linked to alcohol consumption. The risk is particularly high if we consume large amounts of alcohol over many years. This risk is amplified dramatically if we combine drinking with smoking, creating a potent cocktail of irritants for our esophagus.
Moreover, alcohol makes our esophagus more vulnerable to the damaging effects of acid reflux — a significant risk factor for another type of esophageal cancer called adenocarcinoma.
Our stomachs are not exempt from alcohol's reach either. The stomach is our body's food processor — it breaks down what we eat and drink, preparing it to be used for energy. However, alcohol can disrupt the stomach's protective lining, making it more susceptible to the harmful effects of its own digestive juices. This can lead to ulcers and gastritis, an inflammation of the stomach lining. Both conditions increase the risk of stomach cancer over time.
Moreover, alcohol can act as a solvent, helping other harmful chemicals — such as those from tobacco smoke or certain foods — penetrate the stomach lining, further increasing the risk.
Chronic heavy drinking also affects the stomach’s balance of acids and enzymes, disrupting digestion and leading to malnutrition. At the same time, alcohol's diuretic effect can lead to dehydration, which slows the removal of harmful substances from the stomach, prolonging their contact with the stomach lining.
Alcohol's journey through our bodies doesn't end at the throat or stomach. It also impacts our colon and rectum, where it can increase the risk of colorectal cancer. Studies suggest that alcohol's carcinogenic byproducts, including acetaldehyde, can damage DNA and proteins in our colon and rectum, leading to abnormal cell growth and, potentially, cancer.
Finally, we come to pancreatic cancer. The pancreas is a vital organ in our body with two primary roles: aiding digestion and regulating blood sugar. Despite not being as direct or common as with some other cancers, the link between alcohol and pancreatic cancer is worth looking into.
With chronic alcohol consumption, the pancreas can become inflamed, a condition known as pancreatitis. While acute pancreatitis is usually a short-term illness, it can become chronic with continued drinking. Over time, the constant inflammation and damage can cause DNA changes that lead to abnormal cell growth and, potentially, to cancer.

That's some heavy stuff, right? But here's the silver lining: we have the power to lower our risk with these simple, concrete steps:
The important thing is, every step we take towards reducing our alcohol intake is a victory. It's not about doing it perfectly—it's about making progress.