The Risks of Mixing Alcohol and Codeine
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You’re at a friend’s party, and they offer you a drink. But wait. You were up all night coughing last night and took some cough medicine in the middle of the night. Is it okay to drink if you had cough medicine only a few hours earlier? In fact, you might even take another dose tonight just to be safe. Should you take the drink or opt for water?
In this article, we’ll discuss all the reasons why the answer is water.
Codeine is an opiate painkiller used in hospitals to treat pain, but it is also used as an ingredient in some cough suppressants. Codeine is a Schedule 3 drug, meaning it is highly addictive and therefore a controlled substance. It works by suppressing the area of the brain that makes us cough, thereby reducing the number of times we cough. Codeine is also a central nervous system depressant.
Due to growing fears of opioid addiction, codeine is available by prescription only in the U.S. (e.g., Phenergan with Codeine or Robitussin AC). The codeine in many U.S. cough syrups has been replaced with dextromethorphan (DXM), which is synthetically produced and similar to codeine in its effects on the brain and its risk of abuse.
Cough syrup typically has 15 mg of codeine in a 5-mL spoonful. A serving size of cough syrup is typically around 10 mL (30 mg codeine) taken every few hours or 24 hours, depending on the brand. Most cough syrup brands also contain about 10% alcohol, which is used as a solvent or preservative.
Because of the effects of codeine or dextromethorphan on the brain, taking large amounts of cough syrup can actually make you feel drunk.
When used as intended, cough syrup won’t hurt you. However, ingesting more than prescribed means we are ingesting more codeine than we’re supposed to, which can have some pretty nasty side effects. Let’s take a look at some of the common ones:
Ingesting more codeine (or DXM) than prescribed increases the risk of overdose, but how much do we need to take to see these effects? Well, a safe dose is considered no more than 30 mg over 24 hours, and ingesting anything over 300 mg is overdose territory.
But what happens if we take the correct amount and have alcohol with it? Can we mix codeine and alcohol?
It is best to avoid alcohol while taking cough medicine that contains codeine or DXM. For one thing, if you’re coughing, you’re probably sick, which means you should avoid alcohol for the time being anyway. If you combine both substances, it can lead to some adverse health effects:
If you or anyone you know has ingested this combination and has any of these side effects, seek medical attention.
Now, let’s go back to our friend’s party. Has it been long enough since we took the cough medicine, or should we wait? The half-life of codeine in the body is around three hours, so it takes around half a day for it to be out of our system. That said, it is best to wait at least 24 hours before consuming alcohol. Better yet, wait until your cough is completely gone, and opt for a mocktail while you wait!
Now that we’ve unpacked the effects of alcohol while taking cough syrup, let’s look at what happens if we mix them on purpose. Unfortunately, mixing codeine or DXM cough syrup with alcohol has become popular in the past couple of decades, especially among young people, who have nicknamed the mixture “Lean,” “Purple Drank,” or “Sizzurp.” Let’s take a closer look at the dangers.
Now that we’re equipped with all our new slang, let’s unpack it a bit more. Drinking or sipping Lean is basically a way for people to use cough syrup as a recreational drug – they drink Purple Drank with the intent to get high. Remember how we said ingesting anything over 300 mg is getting into overdose territory? Well, that’s how much codeine or DXM cough syrup it takes to get high. That means we’d need to ingest ten times the serving size in 24 hours to get “drunk” off cough syrup.
But why drink Lean? Why not just do shots or a beer bong? The rising popularity of it is largely because it gets people “high” (rather than just drunk) in a more accessible way than other opioids like morphine or illegal drugs like heroin. It’s much easier, cheaper, and safer to purchase cough syrup at the pharmacy than to purchase from a dealer in a dark alley. Plus, it’s much less conspicuous.
We’ve said drinking Lean is dangerous, but what’s so bad about it? Let’s take a look:
With these effects in mind, it’s important to note that ingesting Lean can be fatal. If you or a friend has ingested Lean, call poison control at 800-222-1222 (in the U.S.).
What about cough drops? Do the same dangers apply? The good news is that most cough drop brands contain menthol as their active ingredient (which is not dangerous when mixed with alcohol). Some brands, however, contain DXM (not codeine), so it’s important to check the ingredients or ask your doctor about any possible interactions. But we can’t stress this enough: if you’re coughing or have a sore throat, it’s best to avoid alcohol anyway.
Now that we’ve investigated alcohol and codeine, DXM, and cough syrup from various angles, let’s talk about some things we can do to stay safe.
Whether intentional or accidental, mixing cough medicine and alcohol is dangerous. Understanding these dangers and being vigilant about medication labels and cocktail mixes will help keep us safe. No drink is worth the horrible side effects caused by mixing with codeine or DXM, and our body deserves better, especially when we’re sick.
1. How much cough syrup can make you drunk?
Taking over 300 mg of codeine or DXM cough syrup (10 times the serving size) is typically how much it takes to get “drunk” (or high).
2. Why do people drink Lean?
Drinking Lean became popular in the ‘90s as a way for young people to get high on a budget and in a more accessible way than doing illegal street drugs.
3. Does cough medicine have codeine?
Cough medicine containing codeine has become prescription-only in the U.S. OTC brands replaced it with dextromethorphan (DXM).
4. What is Purple Drank?
Purple Drank, or Lean, is a mixture of cough syrup (with codeine or DXM), soda, candy, and alcohol.
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